Advertisement

Prophylactic Antibiotic Use in Patients with Rheumatic Diseases

Chapter

Abstract

Patients with RA who undergo total hip or knee replacement are at increased risk for prosthetic joint infection, which is further increased in the setting of revision arthroplasty and a previous prosthetic joint infection “as reported by Poss et al. (Clin Orthop 182:117–126, 1984) and Bongartz et al. (Arthritis Rheum. 59(12):1713–20, 2008).” Perioperative prophylactic measures and vigilance during the postoperative period are important in assuring good outcomes in such patients.

Keywords

Prophylactic antibiotics Iatrogenic infection Septic arthritis 

References

  1. 1.
    Poss R, Thornhill TS, Ewald FC, Thomas WH, Batte NJ, Sledge CB. Factors influencing the incidence and outcome of infection following total joint arthroplasty. Clin Orthop. 1984;182:117–26.PubMedGoogle Scholar
  2. 2.
    Bongartz T, Halligan CS, Osmon DR, Reinalda MS, Bamlet WR, Crowson CS, Hanssen AD, Matteson EL. Incidence and risk factors of prosthetic joint infection after total hip or knee replacement in patients with rheumatoid arthritis. Arthritis Rheum. 2008;59(12):1713–20.PubMedCrossRefGoogle Scholar
  3. 3.
    Jamsen E, Huhtala H, Puolakka T, Moilanen T. Risk factors for infection after knee arthroplasty: a register-based analysis of 43,149 cases. J Bone Joint Surg Am. 2009;91:38–47.PubMedCrossRefGoogle Scholar
  4. 4.
    Peersman G, Laskin R, Davis J, Peterson M. Infection in total knee replacement: a retrospective review of 6489 total knee replacements. Clin Orthop Relat Res. 2001;392:15–23.PubMedCrossRefGoogle Scholar
  5. 5.
    Pulido L, Ghanem E, Joshi A, Purtill JJ, Parvizi J. Periprosthetic joint infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res. 2008;466:1710–5.PubMedCrossRefGoogle Scholar
  6. 6.
    Choong PF, Dowsey MM, Carr D, Daffy J, Stanley P. Risk factors associated with acute hip prosthetic joint infections and outcome of treatment with a rifampin-based regimen. Acta Orthop. 2007;78:755–65.PubMedCrossRefGoogle Scholar
  7. 7.
    Phillips JE, Crane TP, Noy M, Elliott TS, Grimer RJ. The incidence of deep prosthetic infections in a specialist orthopaedic hospital: a 15-year prospective survey. J Bone Joint Surg Br. 2006;88:943–8.PubMedCrossRefGoogle Scholar
  8. 8.
    Gilson M, Gossec L, Mariette X, Gherissi D, Guyot MH, Berthelot JM, Wendling D, Michelet C, Dellamonica P, Tubach F, Dougados M, Salmon D. Risk factors for total joint arthroplasty infection in patients receiving tumor necrosis factor α-blockers: a case-control study. Arthritis Res Ther. 2010;12(4): R145.PubMedCrossRefGoogle Scholar
  9. 9.
    Grennan DM, Gray J, Loudon J, et al. Methotrexate and early postoperative complications in patients with rheumatoid arthritis undergoing elective orthopedic surgery. Ann Rheum Dis. 2001;60:214.PubMedCrossRefGoogle Scholar
  10. 10.
    den Broeder AA, Creemers MC, Fransen J, de Jong E, de Rooij DJ, Wymenga A, de Waal-Malefijt M, van den Hoogen FH. Risk factors for surgical site infections and other complications in elective ­surgery in patients with rheumatoid arthritis with special attention for anti-tumor necrosis factor: a large retrospective study. J Rheumatol. 2007;34(4):689–95.Google Scholar
  11. 11.
    Momohara S, Kawakami K, Iwamoto T, Yano K, Sakuma Y, Hiroshima R, Imamura H, Masuda I, Tokita A, Ikari K. Prosthetic joint infection after total hip or knee arthroplasty in rheumatoid arthritis patients treated with nonbiologic and biologic disease-modifying antirheumatic drugs. Mod Rheumatol. 2011;21(5):469–75.PubMedCrossRefGoogle Scholar
  12. 12.
    Solomon DH, Losina E, Baron JA, Fossel AH, Guadagnoli E, Lingard EA, Miner A, Phillips CB, Katz JN. Contribution of hospital characteristics to the volume-outcome relationship: dislocation and infection following total hip replacement surgery. Arthritis Rheum. 2002;46(9):2436–44.PubMedCrossRefGoogle Scholar
  13. 13.
    Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007;116(15):1736–54.PubMedCrossRefGoogle Scholar
  14. 14.
    Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. American Heart Association Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. American Heart Association. J Am Dent Assoc. 2008;139(Suppl):3S–24.PubMedGoogle Scholar
  15. 15.
    Bratzler DW, Houck PM, Surgical Infection Prevention Guidelines Writers Workgroup, et al. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis. 2004;38:1706.PubMedCrossRefGoogle Scholar
  16. 16.
    American Academy of Orthopaedic Surgeons (AAOS). Advisory Statement. Recommendations for the use of intravenous antibiotic prophylaxis in primary total joint arthroplasty 2004. http://www.aaos.org/about/papers/advistmt/1027.asp. Accessed 2 Mar, 2011.
  17. 17.
    Antimicrobial prophylaxis for surgery. Treat Guidel Med Lett 2006; 4:83.Google Scholar
  18. 18.
    Bratzler DW, Hunt DR. The surgical infection prevention and surgical care improvement projects: national initiatives to improve outcomes for patients having surgery. Clin Infect Dis. 2006;43:322.PubMedCrossRefGoogle Scholar
  19. 19.
    Berbari EF, Hanssen AD, Duffy MC, Ilstrup DM, Harmsen WS, Osmon DR. Risk factors for prosthetic joint infection: case-control study. Clin Infect Dis. 1998;27:1247–54.PubMedCrossRefGoogle Scholar
  20. 20.
    Wahl MJ. Myths of dental-induced prosthetic joint infections. Clin Infect Dis. 1995;20(5):1420–5.PubMedCrossRefGoogle Scholar
  21. 21.
    American Dental Association; American Academy of Orthopedic Surgeons. Antibiotic prophylaxis for dental patients with total joint replacements. J Am Dent Assoc. 2003;134:895–8.Google Scholar
  22. 22.
    American Academy of Orthopedic Surgeons. Information statement: prophylaxis for bacteremia in patients with joint replacements. http://www.aaos.org/about/papers/advistmt/1033.asp. Accessed 2 Mar, 2011.
  23. 23.
    American Urological Association. American Academy of Orthopaedic Surgeons Antibiotic prophylaxis for urological patients with total joint replacements. J Urol. 2003;169(5):1796–7.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  1. 1.Department of Infectious DiseasesCleveland ClinicClevelandUSA

Personalised recommendations