Neuroimmunological Molecules and Translational Medicine
Basic neuroscience is a rapidly moving field, and the nervous system is a vast frontier only a small fraction of which has been explored. The potential for discovery of new molecules and concepts in basic neuroscience to be directly applied to the treatment of human neurological disease is high. However, this potential is not fulfilled as often as possible for a multitude of reasons, some of which were dramatized in the recent popular movie “Extraordinary Measures” in which a new enzyme replacement therapy for Pompe’s disease, a glycogen storage disease with dramatic CNS complications, went through a number of hurdles from bench to bedside.
KeywordsExperimental Autoimmune Encephalomyelitis Progressive Multifocal Leukoencephalopathy Enzyme Replacement Therapy Glycogen Storage Disease Progressive Multifocal Leukoencephalopathy
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