High-Frequency Jet Ventilation

  • Martin KeszlerEmail author
  1. I.
    1. A.

      Late rescue treatment: High-frequency jet ventilation (HFJV) has been used extensively for the treatment of refractory respiratory failure unresponsive to conventional mechanical ventilation (CMV). Air leak syndrome has been the most commonly treated underlying disorder, but infants with pulmonary hypoplasia secondary to diaphragmatic hernia, respiratory distress syndrome (RDS), meconium aspiration syndrome, and pneumonia are also treated routinely using HFJV with considerable success in the rescue mode.

    2. B.

      Early rescue treatment: HFJV has documented efficacy and is used extensively in the treatment of moderate to severe RDS, pulmonary interstitial emphysema (PIE), large leaks through a bronchopleural fistula (intractable pneumothorax) or tracheoesophageal fistula, abdominal distention with poor chest wall compliance, congenital diaphragmatic hernia, and in patients with meconium aspiration syndrome with or without pulmonary hypertension.

    3. C.

      Prophylactic use:...


Lung Volume Congenital Diaphragmatic Hernia Conventional Mechanical Ventilation Conventional Ventilation High Peep 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Donn SM, Zak LK, Bozynski MEA, et al. Use of high-frequency jet ventilation in the management of congenital tracheo-esophageal fistula associated with respiratory distress syndrome. J Pediatr Surg. 1990;25:1219–22.PubMedCrossRefGoogle Scholar
  2. Engle WA, Yoder MC, et al. Controlled prospective randomized comparison of HFJV and CV in neonates with respiratory failure and persistent pulmonary hypertension. J Perinatol. 1997;17:3–9.PubMedGoogle Scholar
  3. Gonzalez F, Harris T, Black P, et al. Decreased gas flow through pneumothoraces in neonates receiving high-frequency jet versus conventional ventilation. J Pediatr. 1987;110:464–6.PubMedCrossRefGoogle Scholar
  4. Harris TR, Bunnell JB. High-frequency jet ventilation in clinical neonatology. In: Pomerance JJ, Richardson CJ, editors. Neonatology for the clinician. Norwalk, CT: Appleton & Lange; 1993. p. 311–24.Google Scholar
  5. Keszler M. High-frequency ventilation: evidence-based practice and specific clinical indications. NeoReviews. 2006;7(5):e234–49.CrossRefGoogle Scholar
  6. Keszler M, Donn S, Bucciarelli R, et al. Multi-center controlled trial of high-frequency jet ventilation and conventional ventilation in newborn infants with pulmonary interstitial emphysema. J Pediatr. 1991;119:85–93.PubMedCrossRefGoogle Scholar
  7. Keszler M, Durand D. High-frequency ventilation: past, present, and future. Clin Perinatol. 2001;28:579–607.PubMedCrossRefGoogle Scholar
  8. Keszler M, Modanlou HD, Brudno DS, et al. Multi-center controlled clinical trial of high frequency jet ventilation in preterm infants with uncomplicated respiratory distress syndrome. Pediatrics. 1997;100:593–9.PubMedCrossRefGoogle Scholar
  9. Sugiura M, Nakabayashi H, Vaclavik S, Froese AB. Lung volume maintenance during high frequency jet ventilation improves physiological and biochemical outcome of lavaged rabbit lung. Physiologist. 1990;33:A123.Google Scholar
  10. Wiswell TE, Graziani LJ, Kornhauser MS, et al. Effects of hypocarbia on the development of cystic periventricular leukomalacia in premature infants treated with high-frequency jet ventilation. Pediatrics. 1996a;98:918–24.PubMedGoogle Scholar
  11. Wiswell TE, Graziani LJ, Kornhauser MS, et al. High-frequency jet ventilation in the early management of respiratory distress syndrome is associated with a greater risk for adverse outcomes. Pediatrics. 1996;98:1035–43.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of PediatricsWomen and Infants’ Hospital of Rhode Island, Brown UniversityProvidenceUSA

Personalised recommendations