Form of mechanical ventilation, where tidal volume is the primary target variable and pressure is permitted to fluctuate to deliver this volume.
Although tidal volume may be monitored at the ventilator, measurement at the proximal airway is more accurate and safer for the neonatal patient.
Because uncuffed endotracheal tubes are used in newborns, there may be a variable loss of delivered gas volume from leaks. It is, thus, more appropriate to describe this form of ventilation as volume-controlled, volume-limited, or volume-targeted, rather than volume-cycled ventilation.
Modes which can be utilized with volume-targeted ventilation
Intermittent mandatory ventilation (IMV)
Synchronized intermittent mandatory ventilation (SIMV)
With pressure support (PSV)
Pressure-regulated volume control (PRVC)
Volume-assured pressure support (VAPS)
Mandatory minute ventilation (MMV)
KeywordsTidal Volume Pressure Support Flow Waveform Inspiratory Time Proximal Airway
- Donn SM. Alternatives to ECMO. Arch Dis Child. 1994;70:F81–84.Google Scholar
- Donn SM, Becker MA. Baby in control: neonatal pressure support ventilation. Neonatal Intensive Care. 1998a;11:16–20.Google Scholar
- Donn SM, Becker MA. Mandatory minute ventilation: a neonatal mode of the future. Neonatal Intensive Care. 1998b;11:22–4.Google Scholar
- Donn SM, Sinha SK. Assisted ventilation and its complications. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 8th ed. St. Louis: Elsevier/Mosby; 2011. p. 1116–40.Google Scholar
- Sinha SK, Donn SM, Gavey J, McCarty M. Randomized trial of volume controlled versus time cycled, pressure limited ventilation in preterm infants with respiratory distress syndrome. Arch Dis Child. 1997;77:F202–205.Google Scholar
- Tsai WC, Bandy KP, Donn SM. Volume controlled ventilation of the newborn. In: Donn SM, editor. Neonatal and pediatric pulmonary graphic analysis: principles and clinical applications. Armonk, NY: Futura; 1998. p. 279–300.Google Scholar
- Wheeler K, Klingenberg C, McCallion N, Morley CJ, Davis PG. Volume-targeted versus pressure-limited ventilation in the neonate. Cochrane Database Syst Rev. 2010;(11). Art. No.: CD003666. DOI: 10.1002/14651858.CD003666.pub3.Google Scholar