Volume-Targeted Ventilation

  • Steven M. DonnEmail author
  • Sunil K. Sinha
  1. I.
    1. A.

      Form of mechanical ventilation, where tidal volume is the primary target variable and pressure is permitted to fluctuate to deliver this volume.

    2. B.

      Although tidal volume may be monitored at the ventilator, measurement at the proximal airway is more accurate and safer for the neonatal patient.

    3. C.

      Because uncuffed endotracheal tubes are used in newborns, there may be a variable loss of delivered gas volume from leaks. It is, thus, more appropriate to describe this form of ventilation as volume-controlled, volume-limited, or volume-targeted, rather than volume-cycled ventilation.

  2. II.
    Modes which can be utilized with volume-targeted ventilation
    1. A.

      Intermittent mandatory ventilation (IMV)

    2. B.
      Synchronized intermittent mandatory ventilation (SIMV)
      1. 1.


      2. 2.

        With pressure support (PSV)

    3. C.

      Assist/control (A/C)

    4. D.

      Pressure-regulated volume control (PRVC)

    5. E.

      Volume-assured pressure support (VAPS)

    6. F.

      Mandatory minute ventilation (MMV)

    7. G.

      Volume guarantee...


Tidal Volume Pressure Support Flow Waveform Inspiratory Time Proximal Airway 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Suggested Reading

  1. Bandy KP, Nicks JJ, Donn SM. Volume-controlled ventilation for severe neonatal respiratory failure. Neonatal Intensive Care. 1992;5:70–3.PubMedGoogle Scholar
  2. Donn SM. Alternatives to ECMO. Arch Dis Child. 1994;70:F81–84.Google Scholar
  3. Donn SM, Becker MA. Baby in control: neonatal pressure support ventilation. Neonatal Intensive Care. 1998a;11:16–20.Google Scholar
  4. Donn SM, Becker MA. Mandatory minute ventilation: a neonatal mode of the future. Neonatal Intensive Care. 1998b;11:22–4.Google Scholar
  5. Donn SM, Sinha SK. Assisted ventilation and its complications. In: Martin RJ, Fanaroff AA, Walsh MC, editors. Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 8th ed. St. Louis: Elsevier/Mosby; 2011. p. 1116–40.Google Scholar
  6. Nicks JJ, Becker MA, Donn SM. Neonatal respiratory failure: response to volume ventilation. J Perinatol. 1993;13:72–5.PubMedGoogle Scholar
  7. Sinha SK, Donn SM. Volume- targeted Ventilation. In: Goldsmith JP, Karotkin EH, editors. Assisted Ventilation of the Neonate. 5th ed. St Louis: Saunders Elsevier; 2011. p. 186–99.CrossRefGoogle Scholar
  8. Sinha SK, Donn SM, Gavey J, McCarty M. Randomized trial of volume controlled versus time cycled, pressure limited ventilation in preterm infants with respiratory distress syndrome. Arch Dis Child. 1997;77:F202–205.Google Scholar
  9. Tsai WC, Bandy KP, Donn SM. Volume controlled ventilation of the newborn. In: Donn SM, editor. Neonatal and pediatric pulmonary graphic analysis: principles and clinical applications. Armonk, NY: Futura; 1998. p. 279–300.Google Scholar
  10. Sinha SK, Donn SM. Volume controlled ventilatory modes for the newborn: variations on a theme. Clin Perinatol. 2001;8:547–60.CrossRefGoogle Scholar
  11. Singh J, Sinha SK, Clark P, et al. Mechanical ventilation of very low birthweight infant; Is volume or pressure a better target variable? J Pediatr. 2006;149:308.PubMedCrossRefGoogle Scholar
  12. Singh J, Sinha SK, Donn SM. Volume-targeted ventilation of newborn. Clin Perinatol. 2007;34:93–105.PubMedCrossRefGoogle Scholar
  13. Wheeler K, Klingenberg C, McCallion N, Morley CJ, Davis PG. Volume-targeted versus pressure-limited ventilation in the neonate. Cochrane Database Syst Rev. 2010;(11). Art. No.: CD003666. DOI: 10.1002/14651858.CD003666.pub3.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Neonatal–Perinatal MedicineC.S. Mott Children’s Hospital, F5790 Mott Hospital/5254, University of Michigan Health SystemAnn ArborUSA
  2. 2.Department of Neonatal MedicineThe James Cook University Hospital, University of DurhamMiddlesbroughUK

Personalised recommendations