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The Negative Impact of the Misdiagnosis of Schizophrenia upon Patients, Their Families, and Their Caretakers

  • C. Raymond Lake
Chapter

Abstract

Functionally psychotic patients misdiagnosed with schizophrenia or schizoaffective disorder are most likely to suffer from an undiagnosed psychotic mood disorder or, in a few percent, an unrecognized organic psychosis (Chap. 14 ; Tables 14.1 and 14.2). In either situation, such patients receive substandard care with increased morbidity and mortality. Without a correct diagnosis of a mood disorder, patients are unlikely to receive first-line mood-stabilizing medications, i.e., lithium, valproic acid (Depakote), carbamazepine (Tegretol), and lamotrigine (Lamictal)

Keywords

Bipolar Disorder Mood Disorder Major Depressive Disorder Antipsychotic Medication Tardive Dyskinesia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Anderson, J. (2002, February 26). Witness testifies Yates was insane. Associated Press. www.beliefnet.com/news/2002/03/Witness-Testifies-Yates-Was-Insane.aspx
  2. Angst, J., Weis, P., Grof, P., Baastrup, P. C., & Shou, M. (1970). Lithium prophylaxis in recurrent affective disorders. The British Journal of Psychiatry, 116, 604–614. (Chap. 15).PubMedCrossRefGoogle Scholar
  3. Anonymous. (2006). Children murdered by their Christian parents memorial page. http://myth-one.com/memorial.htm
  4. Artaloytia, J. F., Arango, C., Lahti, A., Sanz, J., Pascual, A., Cubero, P., Prieto, D., & Palomo, T. (2006). Negative signs and symptoms secondary to antipsychotics: a double-blind, randomized trial of a single dose of placebo, haloperidol, and risperidone in healthy volunteers. The American Journal of Psychiatry, 163, 488–493. (Chap. 15).PubMedCrossRefGoogle Scholar
  5. Becker, J., Johnson, K., & Kovaleski, S. F. (2011, January 11). Police say they visited Tucson suspect’s home even before rampage. The New York Times. (Chap. 15, Table 15.51).Google Scholar
  6. Berger, J., & Gross, J. (1998, June 19). From mental illness to Yale to murder charge. The New York Times. (Chap. 15, Table 15.51).Google Scholar
  7. Bleuler, E. (1911/1950). Dementia praecox or the group of schizophrenias. New Yrok: International Universities Press.Google Scholar
  8. Bourget, D., Grace, J., & Whitehurst, L. (2007). A review of maternal and paternal filicide. Journal of American Academic Psychiatry Law, 35, 74–82. (Chap. 15).Google Scholar
  9. Boyer, W. F., Bakalar, N. H., & Lake, C. R. (1987). Anticholinergic prophylaxis of acute haloperidol-induced acute dystonic reactions. Journal of Clinical Psychopharmacology, 7, 164–166.PubMedGoogle Scholar
  10. Braxton, A. (2011, March 7). Murder/Suicide shocks seventh ward neighborhood. Fox 8 TV, New Orleans. (Chap. 15, Table 15.51).Google Scholar
  11. Calabrese, J. R., Shelton, M. D., Bowden, C. L., Rapport, D. J., Suppes, T., Shirley, E. R., Kimmel, S. E., & Caban, S. J. (2001). Bipolar rapid cycling: Focus on depression as its hallmark. The Journal of Clinical Psychiatry, 62(Suppl 14), 34–41. (Chap. 15).PubMedGoogle Scholar
  12. Carey, B. (2011, June 31). Expert on mental illness reveals her own fight. The New York Times. (Chap. 16, Table 16.31).Google Scholar
  13. Carlson, G. A., & Goodwin, F. K. (1973). The stages of mania. A longitudinal analysis of the manic episode. Archives of General Psychiatry, 28, 221–228. (Chaps. 1, 8).PubMedCrossRefGoogle Scholar
  14. Carpenter, W., McGlashan, T., & Strauss, J. (1977). The treatment of acute schizophrenia without drugs: An investigation of some current assumptions. The American Journal of Psychiatry, 134, 14–20. (Chap. 15).PubMedGoogle Scholar
  15. Casey, D. E. (1988). Affective disorders and tardive dyskinesia. L'Encéphale, XIV, 221–226. (Chap. 15).Google Scholar
  16. Fazel, S., Gulati, G., Linsell, L., Geddes, J. R., & Grann, M. (2009). Schizophrenia and violence: Systematic review and meta-analysis. PLoS Medicine, 6, 1–15.CrossRefGoogle Scholar
  17. Foderaro, L. W. (2000, May 12). Man who killed fiancée is sent to mental hospital. The New York Times. (Chap 15, Table 15.51).Google Scholar
  18. Gershon, S., & Yuwiler, A. (1960). Lithium ion: A specific psychopharmacological approach to the treatment of mania. Journal of Neuropsychiatry, 1, 229–241.PubMedGoogle Scholar
  19. Goodwin, F. K. (1989). The biology of recurrence: New directions for the pharmacologic bridge. The Journal of Clinical Psychiatry, 50, 40–44. (Chaps. 8, 9, 10, 18).PubMedGoogle Scholar
  20. Goodwin, F. K., & Jamison, K. R. (1990). Manic-depressive illness. New York: Oxford University Press.Google Scholar
  21. Goodwin, F. K., & Jamison, K. R. (2007). Manic-depressive illness. New York: Oxford University Press.Google Scholar
  22. Hartocollis, A. (2007, May 24). Writer is convicted in sex attack on former colleague. The New York Times. (Chap. 15, Table 15.51).Google Scholar
  23. Insel, T. R. (2010). Rethinking schizophrenia. Nature, 468, 187–193.PubMedCrossRefGoogle Scholar
  24. Jimenez-Jimenez, F. J., Garcia-Ruiz, P. J., & Molina, J. A. (1997). Drug-induced movement disorders. Drug Safety, 16, 180–204. (Chap. 15).PubMedCrossRefGoogle Scholar
  25. Johnson, K., Kovaleski, S. F., Frosch, D., Lipton, E. (2011, January 10). Alarm grew at suspect’s disturbing behavior. The New York Times. (Chap. 15, Table 15.51).Google Scholar
  26. Kessing, L. V., & Anderson, P. K. (2004). Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder? Journal of Neurology, Neurosurgery, and Psychiatry, 75, 1662–1666. (Chap. 15).PubMedCrossRefGoogle Scholar
  27. Lake, C. R. (2008c). How academic psychiatry can better prepare our students for their future patients: Part I: The failure to recognize depression and risk for suicide in primary care; problem identification, responsibility and solutions. Behavioral Medicine, 34, 95–100.PubMedCrossRefGoogle Scholar
  28. Lake, C. R. (2008d). How academic psychiatry can better prepare our students for their future patients: Part II: A course in ultra-brief initial diagnostic screening suitable for future primary care physicians. Behavioral Medicine, 34, 101–116.PubMedCrossRefGoogle Scholar
  29. Lake, C. R., & Baumer, J. (2010). Academic psychiatry’s responsibility for increasing the recognition of mood disorders and risk for suicide in primary care. Current Opinion in Psychiatry, 23, 157–166.PubMedCrossRefGoogle Scholar
  30. Longman, J. (2010, December 10). John E. du Pont, 72, dies; killed athlete. The New York Times. (Chap. 15, Table 15.51).Google Scholar
  31. Mandal, V. (2002, October 7). Families of mentally ill pay terrible toll: Psychiatric patients are killing and assaulting their families at an alarming rate. Vancouver Sun. (Chap. 15, Table 15.51).Google Scholar
  32. Mann, D. (2009, December 1). The case of Otty Sanchez. The StandDown Texas Project. (Chap. 15, Table 15.53).Google Scholar
  33. Mann, D. (2010, January 13). Gone baby gone. The Texas Observer. (Chap. 15, Table 15.53).Google Scholar
  34. McEvoy, J. P., et al. (2005). Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANESIII. Schizophrenia Research, 80, 19–32.PubMedCrossRefGoogle Scholar
  35. Pini, S., Cassano, G. B., Dell’Osso, L., & Amador, X. F. (2001). Insight into illness in schizophrenia, schizoaffective disorder, and mood disorders with psychotic features. The American Journal of Psychiatry, 158, 122–125. (Chaps. 8, 9).PubMedCrossRefGoogle Scholar
  36. Pope, H. G. (1983). Distinguishing bipolar disorder from schizophrenia in clinical practice: Guidelines and case reports. Hospital & Community Psychiatry, 34, 322–328. (Chaps. 1, 8).Google Scholar
  37. Post, R. M. (1992). Transduction of psychosocial stress into the neurobiology of recurrent affective disorder. The American Journal of Psychiatry, 149, 999–1010. (Chap. 8).PubMedGoogle Scholar
  38. Post, R. M. (2007). The case for polypharmacy in the treatment of bipolar disorder. Psychiatric Times, 24, 1–4.Google Scholar
  39. Post, R. M. (2010). Overlaps between schizophrenia and bipolar disorder. Psychiatric Annals, 41, 106–112.CrossRefGoogle Scholar
  40. Prien, R. F., Caffey, E. M., Jr., & Klett, C. J. (1972). A comparison of lithium carbonate and chlorpromazine in the treatment of excited schizo-affectives. Archives of General Psychiatry, 27, 182–189. (Chap. 9).PubMedCrossRefGoogle Scholar
  41. Prien, R. F., Klett, C. J., & Caffey, E. M., Jr. (1973). Lithium carbonate and imipramine in prevention of affective episodes: A comparison in recurrent affective illness. Archives of General Psychiatry, 29, 420–425.PubMedCrossRefGoogle Scholar
  42. Prien, R. F., Kupfer, D. J., Mansky, P. A., et al. (1984). Drug therapy in the prevention of recurrences in unipolar and bipolar affective disorders: Report of the NIMH Collaborative Study Group comparing lithium carbonate, imipramine, and a lithium carbonate-imipramine combination. Archives of General Psychiatry, 41, 1096–1104.PubMedCrossRefGoogle Scholar
  43. Quitkin, F. M., Kane, J., Rifkin, A., et al. (1981). Prophylactic lithium carbonate with and without imipramine for bipolar I patients: A double-blind study. Archives of General Psychiatry, 38, 902–907.PubMedCrossRefGoogle Scholar
  44. Rosack, J. (2006). Patient charged with murder of schizophrenia expert. Psychiatric News, 41, 1. (Chap. 15, Table 15.51).Google Scholar
  45. Schou, M. (1967). Therapeutic and prophylactic action of lithium aga. Activitas Nervosa Superior, 9, 440. (Chap. 15).PubMedGoogle Scholar
  46. Schou, M. (1968). Special review: Lithium in psychiatric therapy and prophylaxis. Journal of Psychiatric Research, 6, 67–95. (Chap. 15).PubMedCrossRefGoogle Scholar
  47. Schou, M. (1979). Lithium as a prophylactic agent in unipolar affective illness: Comparison with cyclic antidepressants. Archives of General Psychiatry, 36, 849–851. (Chap. 15).PubMedCrossRefGoogle Scholar
  48. Sernyak, M. J., Griffin, R. A., Johnson, R. M., Pearsall, H. R., Wexler, B. E., & Woods, S. W. (1994). Neuroleptic exposure following inpatient treatment of acute mania with lithium and neuroleptic. The American Journal of Psychiatry, 151, 133–135. (Chap. 15).PubMedGoogle Scholar
  49. Shapiro, D. R., Quitkin, F. M., & Fleiss, J. L. (1989). Response to maintenance therapy in bipolar illness: Effect of index episode. Archives of General Psychiatry, 46, 401–405.PubMedCrossRefGoogle Scholar
  50. Shopsin, B., Kim, S. S., & Gershon, S. (1971). A controlled study of lithium vs chlorpromazine in acute schizophrenics. The British Journal of Psychiatry, 119, 435–440. (Chap. 15).PubMedCrossRefGoogle Scholar
  51. Swartz, C. M. (1995). Tardive psychopathology. Neuropsychobiology, 32, 115–119. (Chap. 12).PubMedCrossRefGoogle Scholar
  52. Tyler, P., & Kendall, T. (2009). The spurious advance of antipsychotic drug therapy. The Lancet, 373, 1007.Google Scholar
  53. Walsh, D. (2002, March 15). The murder conviction of Andrea Yates: A tragic case, a barbaric verdict. World Socialist Web Site. (Chap. 15, Table 15.53).Google Scholar
  54. Wehr, T. A., & Goodwin, F. K. (1987). Can antidepressants cause mania and worsen the course of affective illness? The American Journal of Psychiatry, 144, 1403–1411.PubMedGoogle Scholar
  55. Whitaker, R. (2004). The case against antipsychotic drugs: A 50-year record of doing more harm than good. Medical Hypotheses, 62, 5–13.PubMedCrossRefGoogle Scholar
  56. Wikipedia. (2011). On-line encyclopedia. Wikipedia.org.2011.Google Scholar
  57. Zarate, C. A., Jr., & Tohen, M. (2004). Double-blind comparison of the continued use of antipsychotic treatment versus its discontinuation in remitted manic patients. The American Journal of Psychiatry, 161, 169–171. (Chap. 15).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department Psychiatry and Behavioral SciencesUniversity of Kansas, School of MedicineKansas CityUSA

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