Selenium pp 335-344 | Cite as

An Emerging Picture of the Biological Roles of Selenoprotein K



Recent insight has been made regarding the biological role(s) for selenoprotein K (SelK) in humans and other organisms. Suggested functions for mammalian SelK include protection against oxidative stress in cardiomyocytes, regulation of endoplasmic reticulum (ER) stress in HepG2 cells, and facilitation of calcium flux in immune cells during receptor-mediated activation. The data supporting these functions as well as other aspects of SelK are summarized in this chapter.


Endoplasmic Reticulum HepG2 Cell Endoplasmic Reticulum Stress West Nile Virus Endoplasmic Reticulum Membrane 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Cell and Molecular Biology, John A. Burns School of MedicineUniversity of HawaiiHonoluluUSA

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