Thyroid Cancer pp 201-205 | Cite as

Thyroid Lymphoma

Part of the Endocrine Updates book series (ENDO, volume 32)


Although the incidence (or at least the clinical presentation) of thyroid malignancies has been increasing in recent years, clinically significant thyroid cancers remain far less common than autoimmune thyroid diseases, Graves’ disease, and Hashimoto’s thyroiditis. Further, of the different pathological types of thyroid cancer, thyroid lymphomas are rare, representing less than 5% of thyroid neoplasms. Therefore, thyroid lymphomas are only encountered infrequently in clinical practice, for example, approximately two patients per year in a major referral center. Nevertheless, awareness and recognition of this condition are important because it is typically symptomatic and it may be amenable to therapy. Lymphomatous involvement of the thyroid gland can be localized to the gland (“primary”) or may be one component of more widespread lymphoma. This distinction may sometimes be blurred when the disease is primarily located in the thyroid but is also present to a limited extent in other regions, such as in lymph nodes adjacent to the thyroid. Viewed from another perspective, less than 1% of non-Hodgkin lymphomas present with primary thyroid involvement.


Autoimmune thyroid diseases B-cell Graves’ disease Hashimoto’s thyroiditis MALT Thyroid neoplasms Treatment of lymphoma 


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Endocrinology, Diabetes, and Metabolism, Department of MedicineCedars-Sinai Medical CenterLos AngelesUSA

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