High-Throughput Sequencing Data Analysis Software: Current State and Future Developments
In previous chapters of this book, there is detailed treatment of the technicalities of such problems as de novo sequence assembly and sequence alignment. In this chapter, we take a different perspective. Drawing on nearly a decade of the authors’ collective experience in providing bioinformatics support to bench-based biologists, we focus on the practical applications and on the biologist end-user’s experience. We attempt to make some observations, speculations and recommendations that might help the “wet” biologist who wishes to take responsibility for dealing their own data.
KeywordsSequence Assembly Alignment Tool Reference Genome Sequence Assembly Tool Pacific Bioscience
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