Abstract
Many factors are likely to significantly affect the outcome of a bioenhanced primary repair of the ACL. These factors include the choice of implanted scaffold, bioactive agent, and suture technique as only a few variables. In this chapter, we will review how each of these factors influences functional ACL healing in a complete ACL transection model. We will also demonstrate the discovery that by optimizing all of these factors, the current technique of bioenhanced ACL repair used in our laboratory results in a healing ACL with equal strength to an ACL reconstruction after 3 months of healing in a large animal model. These findings provide hope that 1 day, bioenhanced ACL repair will be a viable option for patients with ACL injuries.
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Acknowledgement
Research reported in this chapter was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award Number RO1-AR054099. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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Haslauer, C.M., Murray, M.M. (2013). Can We Get a Complete ACL Tear to Heal?. In: Murray, M., Vavken, P., Fleming, B. (eds) The ACL Handbook. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0760-7_16
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DOI: https://doi.org/10.1007/978-1-4614-0760-7_16
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