Application of Optical Coherence Tomography in Neuro-Ophthalmic Disorders
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Optical coherence tomography (OCT) is an evolving technology, developed in the 1990s to provide noninvasive imaging of tissues. Using low-coherence light and ultra-short laser pulses, it generates cross-sectional images of biologic structures with great detail. OCT has become valuable in medicine, especially in ophthalmology. This technology allows the detection of early or subtle pathology and provides a critical tool in the diagnosis and management of ocular diseases. OCT is routinely used in the fields of retina and glaucoma, and now has become more popular in neuro-ophthalmology. In this chapter the role of OCT technology, its limitations, and use in the differentiation of optic nerve disorders from retinal disorders will be discussed. Its potential role in the diagnosis and monitoring of multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease will also be highlighted.
KeywordsOptical Coherence Tomography Retinal Nerve Fiber Layer Optic Neuritis Retinal Nerve Fiber Layer Thickness Spectral Domain Optical Coherence Tomography
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