Abstract
Dynamical spectroscopy of intensity fluctuations allows measurements of the dynamic scattering of light and motility detection of biomicroparticles in suspensions and tissues. Spectroscopy of intensity fluctuations allows the detection of complex rhythms of the rat heart in vitro. The optical portable spectrometer used detected Fourier spectra and real-time rhythms in rat cardiomyocytes, the beating in the infarct model of the rat heart. The findings indicated that single cardiomyocyte beating was superimposed on the autowave heart tissue rhythm and associated with the apoptotic process. A dependence was observed of the superposition of individual cardiomyocyte beatings at 8–22 Hz on their metabolic state and autooscillations of isolated rat heart tissue at 1–2 Hz.
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References
Norina S, Kim J, Soh KS (2007) Gradient magnetic field effects on separation, Fourier-spectra and motion of chromatin particles and cells. Int J Appl Electromagn Mech 25(1–4):419–427
Norina S, Kim J, Yang JM et al (2007) Spectroscopy of intensity fluctuations of cell dynamics, tissue reflectance and auto-fluorescence. In: R. Magjarevic and J.H. Nagel (eds) World congress on medical physics and biomedical engineering 2006. Springer, Heidelberg, pp 1324–1326
Maruyama R, Takemura G, Tohse N et al (2006) Synchronous progression of calcium transient-dependent beating and sarcomere destruction in apoptotic adult cardiomyocytes. Am J Physiol Heart Circ Physiol 290:H1493–H1502
Zimnyakov DA, Tuchin VV (2003) Speckle correlometry. In: Tuan Vo-Dinh Chief (ed) Biomedical photonics handbook. SPIE Press, Bellingham, pp 14-1–14-20
Rastopov S (2004) US Patent Application 20040070756
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Norina, S., Lee, B.C., Kim, J., Baek, K.Y. (2012). Apoptotic Cardiomyocyte Beating Frequency Detected with Optical Intensity Fluctuation Spectrometer. In: Soh, KS., Kang, K., Harrison, D. (eds) The Primo Vascular System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0601-3_36
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DOI: https://doi.org/10.1007/978-1-4614-0601-3_36
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