Obesity, Type 2 Diabetes and Cancer

  • Rosalyn D. Ferguson
  • Derek LeRoithEmail author
Part of the Cancer Drug Discovery and Development book series (CDD&D)


A large percentage of the developed world’s population is now either officially overweight or obese; meanwhile, cancer rates have been rising steadily. Cases of type 2 diabetes have also become alarmingly common. In this chapter, we discuss the epidemiological evidence which suggests that obesity, type 2 diabetes and ­cancer are linked. Possible mechanisms for obesity leading to type 2 diabetes and cancer are discussed, as well as the recent studies which potentially uncover ­therapies to treat aspects and reduce the rates of cancer associated with obesity and type 2 diabetes.


Breast Cancer Prostate Cancer Insulin Resistance Adipose Tissue Glargine Insulin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Division of Endocrinology, Diabetes and Bone Diseases, The Samuel Bronfman Department of MedicineMount Sinai School of MedicineNew YorkUSA

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