Abstract
Long acting injections and implants emerged as a sub-area of pharmaceutics in the twentieth century, with companies dedicated to the field being established in the 1960s and 1970s. The field contains a wide range of system types. This chapter summarizes the historical development of the field, including rate-controlled membrane concepts, biodegradable polymer concepts, surface-releasing systems, liposomes, targeted/nanoscale systems, and microelectronic systems.
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Wright, J.C., Hoffman, A.S. (2012). Historical Overview of Long Acting Injections and Implants. In: Wright, J., Burgess, D. (eds) Long Acting Injections and Implants. Advances in Delivery Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0554-2_2
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DOI: https://doi.org/10.1007/978-1-4614-0554-2_2
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