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Microsphere Technologies

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Long Acting Injections and Implants

Part of the book series: Advances in Delivery Science and Technology ((ADST))

Abstract

This chapter, divided into three sections, discusses important developments in microsphere technology for parenteral drug delivery. In the first section, microsphere systems are briefly described and polymers including both natural and synthetic polymers used in microsphere technology are reviewed. In the second section, various conventional microsphere fabrication methods as well as recent advances in microsphere preparation methods are discussed. Specific examples of microsphere applications, including microspheres for small molecules, protein therapeutics and vaccines are provided. In the final section, some of the challenges associated with developing microsphere products and means to overcome these challenges are discussed.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, School of Pharmacy, University of Connecticut, 69 N Eagleville Rd U3092, Storrs, CT, 06269, USA

    Yan Wang & Diane J. Burgess

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  1. Yan Wang
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  2. Diane J. Burgess
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Correspondence to Diane J. Burgess .

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    Jeremy C. Wright

  2. Browns Road 626, Storrs, 06268, Connecticut, USA

    Diane J. Burgess

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Wang, Y., Burgess, D.J. (2012). Microsphere Technologies. In: Wright, J., Burgess, D. (eds) Long Acting Injections and Implants. Advances in Delivery Science and Technology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0554-2_10

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