Abstract
In this chapter, we present on-line testing and test-generation techniques for digital microfluidic biochips. First we present an on-line testing method for digital microfluidic biochips. This method interleaves the implementation of the microfluidic compactor with bioassays in functional mode. An optimization method is presented to schedule logic AND operations in the compactor to minimize the end time for the compaction procedure. Next we present an automatic test pattern generation (ATPG) method for non-regular digital microfluidic chips. The ATPG method can generate test patterns to detect catastrophic defects in non-regular arrays where the full reconfigurability of the digital microfluidic platform is not utilized.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Y. Zhao, K. Chakrabarty, “On-line testing of lab-on-chip using digital microfluidic compactors" in Proceedings of IEEE International On-line Testing, Symposium, 2008, pp. 213–218
Y. Zhao, K. Chakrabarty, On-line testing of lab-on-chip using reconfigurable digital-microfluidic compactors. Int. J. Parallel Prog. 37, 370–388 (2009)
F. Su, S. Ozev, K. Chakrabarty, Concurrent testing of digital microfluidics-based biochips. ACM Trans. Des. Autom. Electron. Syst. 11, 442–464 (2006)
V. Srinivasan, V.K. Pamula, M.G. Pollack, R.B. Fair, Clinical diagnositics on human whole blood, plasma, serum, urine, saliva, sweat, and tears on a digital microfluidic platform in Proceedings of MicroTAS, 2003, pp. 1287–290
Y. Zhao, K. Chakrabarty, Testing of low-cost digital microfluidic biochips with non-regular array layouts in Proceedings of IEEE Asian Test Symposium, 2010)
Advanced Liquid Logic, http://www.liquid-logic.com
F. Su, W. Hwang, A. Mukherjee, K. Chakrabarty, Testing and diagnosis of realistic defects in digital microfluidic biochips. J. Electron. Test. Theory and Appl. 23, 219–233 (2007)
F. Su, S. Ozev, K. Chakrabarty, Test planning and test resource optimization for droplet-based microfluidic systems. J. Electron. Test. Theory Appl. 22, 199–210 (2006)
M.L. Bushnell, V.D. Agrawal, Essentials of Electronic Testing for Digital Memory and Mixed-Signal VLSI Circuits (Kluwer Academic Publishers, Netherlands, 2000)
L. Luan, R.D. Evans, N.M. Jokerst, R.B. Fair, Integrated optical sensor in a digital microfluidic platform. IEEE Sens. J. 8, 628–635 (2008)
E.W. Dijkstra, A note on two problems in connexion with graphs. Numerische Mathematik 1, 269–271 (1959)
R. Sista, Z. Hua, P. Thwar, A. Sudarsan, V. Srinivasan, A. Eckhardt, M.G. Pollack, V.K. Pamula, Development of a digital microfluidic platform for point of care testing. Lab on a Chip 8, 2091–2104 (2008)
Y. Zhao, K. Chakrabarty, Pin-count-aware online testing of digital microfluidic biochips in Proceedings of IEEE VLSI Test Symposium, 2010, pp. 111–116
T. Xu, W. Hwang, F. Su, and K. Chakrabarty, Automated design of pin-constrained digital microfluidic biochips under droplet-interference constraints. ACM J. Emer. Technol. Comput. Syst. 3, 14.1–14.23 (2007)
T. Xu, K. Chakrabarty, Design-for-testability for digital microfluidic biochips in Proceedings of IEEE VLSI Tes, Symposium, 2009, pp. 309–314
T. Xu, K. Chakrabarty, Broadcast electrode-addressing for pin-constrained multi-functional digital microfluidic biochips in Proceedings of IEEE/ACM Design Automation Conference, 2008, pp. 173–178
F. Su, K. Chakrabarty, High-level synthesis of digital microfluidic biochips. ACM J. Emer. Technol. Comput. Syst. 3, 16.1–16.32, 2008
H. Ren, Electrowetting-Based Sample Preparation: An Initial Study for Droplet Transportation, Creation and On-chip Digital Dilution. PhD Thesis, Duke University, Durham, NC, 2004.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this chapter
Cite this chapter
Zhao, Y., Chakrabarty, K. (2013). On-Line Testing and Test Generation. In: Design and Testing of Digital Microfluidic Biochips. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0370-8_6
Download citation
DOI: https://doi.org/10.1007/978-1-4614-0370-8_6
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-0369-2
Online ISBN: 978-1-4614-0370-8
eBook Packages: EngineeringEngineering (R0)