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Rasmussen’s Syndrome

  • David W. McCandlessAffiliated withThe Chicago Medical School Department of Cell Biology and Anatomy, Rosalind Franklin University

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Rasmussen’s syndrome is a childhood developing syndrome, usually characterized by refractory focal motor seizures (epilepsia partialis continua). Most cases originate between the age of 1 and 10 years, mean age about 5 years. Symptoms are attributed to chronic pathogen-free inflammation of both gray and white matter. There is a progressive unihemispheric atrophy (Rasmussen 1978). In 50% of patients, the onset of Rasmussen encephalitis is preceded by an inflammatory episode such as an U.R.I.