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Abstract

Hemifacial spasm (HFS), a syndrome of unilateral facial nerve hyperactive dysfunction, is a severe and disabling condition that causes impairments in the quality of life [1]. The spasms are characterized by slight intermittent twitching of a single facial muscle that gradually becomes more intense and occurs with greater frequency, later spreading to involve the other muscles of facial expression. Ultimately, the patient may develop prolonged contractions of all the involved muscles causing severe, disfiguring grimacing with partial closure of the eye and drawing up of the corner of the mouth, the so-called tonus phenomenon [2]. Typical and atypical variations of the disorder exist. In typical HFS, spasms begin insidiously in the orbicularis oculi muscle and spread over time to the muscles of the face with variable involvement of the frontalis and platysma muscles. Conversely, in atypical HFS, spasms begin insidiously in the muscles of the lower face and spread to the orbicularis oculi muscles over time. Typical HFS occurs much more frequently than atypical HFS [3]. The best available data suggest that the prevalence rate of HFS is 10 patients per 100,000 in the population of the United States and Norway [4, 5].

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References

  1. Deletis V, Urriza J, Ulkatan S, Fernandez-Conejero I, Lesser J, Misita D. The feasibility of recording blink reflexes under general anesthesia. Muscle Nerve. 2009;39(5):642–6.

    Article  PubMed  Google Scholar 

  2. Jannetta PJ, Samii M, editors. The cranial nerves. Berlin: Springer; 1981.

    Google Scholar 

  3. Jannetta PJ. Typical or atypical hemifacial spasm. J Neurosurg. 1998;89(2):346–7.

    PubMed  CAS  Google Scholar 

  4. Auger RG, Whisnant JP. Hemifacial spasm in Rochester and Olmsted County, Minnesota, 1960 to 1984. Arch Neurol. 1990;47(11):1233–4.

    Article  PubMed  CAS  Google Scholar 

  5. Nilsen B, Le KD, Dietrichs E. Prevalence of hemifacial spasm in Oslo, Norway. Neurology. 2004;63(8):1532–3.

    Article  PubMed  Google Scholar 

  6. Marti-Fabregas J, Montero J, Lopez-Villegas D, Quer M. Post-irradiation neuromyotonia in bilateral facial and trigeminal nerve distribution. Neurology. 1997;48(4):1107–9.

    Article  PubMed  CAS  Google Scholar 

  7. Valls-Sole J. Facial palsy, postparalytic facial syndrome, and hemifacial spasm. Mov Disord. 2002;17 Suppl 2:S49–52.

    Article  PubMed  Google Scholar 

  8. Kimura J, Powers JM, Van Allen MW. Reflex response of orbicularis oculi muscle to supraorbital nerve stimulation. Study in normal subjects and in peripheral facial paresis. Arch Neurol. 1969;21(2):193–9.

    Article  PubMed  CAS  Google Scholar 

  9. Nielsen VK. Pathophysiology of hemifacial spasm: II. Lateral spread of the supraorbital nerve reflex. Neurology. 1984;34(4):427–31.

    Article  PubMed  CAS  Google Scholar 

  10. Hopf HC, Lowitzsch K. Hemifacial spasm: location of the lesion by electrophysiological means. Muscle Nerve. 1982;5(9S):S84–8.

    PubMed  CAS  Google Scholar 

  11. Moller AR. Hemifacial spasm: ephaptic transmission or hyperexcitability of the facial motor nucleus? Exp Neurol. 1987;98(1):110–9.

    Article  PubMed  CAS  Google Scholar 

  12. Montero J, Junyent J, Calopa M, Povedano M, Valls-Sole J. Electrophysiological study of ephaptic axono-axonal responses in hemifacial spasm. Muscle Nerve. 2007;35(2):184–8.

    Article  PubMed  CAS  Google Scholar 

  13. Nagatani T, Inao S, Suzuki Y, Yoshida J. Perforating branches from offending arteries in hemifacial spasm: anatomical correlation with vertebrobasilar configuration. J Neurol Neurosurg Psychiatry. 1999;67(1):73–7.

    Article  PubMed  CAS  Google Scholar 

  14. Barker II FG, Jannetta PJ, Bissonette DJ, Shields PT, Larkins MV, Jho HD. Microvascular decompression for hemifacial spasm. J Neurosurg. 1995;82(2):201–10.

    Article  PubMed  Google Scholar 

  15. Sekula Jr RF, Bhatia S, Frederickson AM, et al. Utility of intraoperative electromyography in microvascular decompression for hemifacial spasm: a meta-analysis. Neurosurg Focus. 2009;27(4):E10.

    Article  Google Scholar 

  16. Marelli RA, Hillel AD. Effects of general anesthesia on the human blink reflex. Head Neck. 1989;11(2):137–49.

    Article  PubMed  CAS  Google Scholar 

  17. Mourisse J, Gerrits W, Lerou J, van Egmond J, Zwarts MJ, Booij L. Electromyographic assessment of blink and corneal reflexes during midazolam administration: useful methods for assessing depth of anesthesia? Acta Anaesthesiol Scand. 2003;47(5):593–600.

    Article  PubMed  CAS  Google Scholar 

  18. Mourisse J, Lerou J, Struys M, Zwarts M, Booij L. Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 2. BIS and tetanic stimulus-induced withdrawal reflex. Br J Anaesth. 2007;98(6):746–55.

    Article  PubMed  CAS  Google Scholar 

  19. Mourisse J, Lerou J, Zwarts M, Booij L. Electromyographic assessment of blink reflexes correlates with a clinical scale of depth of sedation/anaesthesia and BIS during propofol administration. Acta Anaesthesiol Scand. 2004;48(9):1174–9.

    Article  PubMed  CAS  Google Scholar 

  20. Moller AR, Jannetta PJ. On the origin of synkinesis in hemifacial spasm: results of intracranial recordings. J Neurosurg. 1984;61(3):569–76.

    Article  PubMed  CAS  Google Scholar 

  21. Moller AR, Jannetta PJ. Hemifacial spasm: results of electrophysiologic recording during microvascular decompression operations. Neurology. 1985;35(7):969–74.

    Article  PubMed  CAS  Google Scholar 

  22. Moller AR, Jannetta PJ. Physiological abnormalities in hemifacial spasm studied during microvascular decompression operations. Exp Neurol. 1986;93(3):584–600.

    Article  PubMed  CAS  Google Scholar 

  23. Yamashita S, Kawaguchi T, Fukuda M, Watanabe M, Tanaka R, Kameyama S. Abnormal muscle response monitoring during microvascular decompression for hemifacial spasm. Acta Neurochir (Wien). 2005;147(9):933–7, discussion 937–8.

    Google Scholar 

  24. Kong DS, Park K, Shin BG, Lee JA, Eum DO. Prognostic value of the lateral spread response for intraoperative electromyography monitoring of the facial musculature during microvascular decompression for hemifacial spasm. J Neurosurg. 2007;106(3):384–7.

    Article  PubMed  Google Scholar 

  25. Sindou MP. Microvascular decompression for primary hemifacial spasm. Importance of intraoperative neurophysiological monitoring. Acta Neurochir (Wien). 2005;147(10):1019–26, discussion 1026.

    Google Scholar 

  26. Hatem J, Sindou M, Vial C. Intraoperative monitoring of facial EMG responses during microvascular decompression for hemifacial spasm. Prognostic value for long-term outcome: a study in a 33-patient series. Br J Neurosurg. 2001;15(6):496–9.

    Article  PubMed  CAS  Google Scholar 

  27. Kiya N, Bannur U, Yamauchi A, Yoshida K, Kato Y, Kanno T. Monitoring of facial evoked EMG for hemifacial spasm: a critical analysis of its prognostic value. Acta Neurochir (Wien). 2001;143(4):365–8.

    Article  CAS  Google Scholar 

  28. Joo WI, Lee KJ, Park HK, Chough CK, Rha HK. Prognostic value of intra-operative lateral spread response monitoring during microvascular decompression in patients with hemifacial spasm. J Clin Neurosci. 2008;15(12):1335–9.

    Article  PubMed  Google Scholar 

  29. Huh R, Han IB, Moon JY, Chang JW, Chung SS. Microvascular decompression for hemifacial spasm: analyses of operative complications in 1582 consecutive patients. Surg Neurol. 2008;69(2):153–7, discussion 157.

    Google Scholar 

  30. Samii M, Gunther T, Iaconetta G, Muehling M, Vorkapic P, Samii A. Microvascular decompression to treat hemifacial spasm: long-term results for a consecutive series of 143 patients. Neurosurgery. 2002;50(4):712–8, discussion 718–9.

    Google Scholar 

  31. Polo G, Fischer C, Sindou MP, Marneffe V. Brainstem auditory evoked potential monitoring during microvascular decompression for hemifacial spasm: intraoperative brainstem auditory evoked potential changes and warning values to prevent hearing loss–prospective study in a consecutive series of 84 patient. Neurosurgery. 2004;54(1):97–104, discussion 104–6.

    Google Scholar 

  32. Currier RD, Dejong RN. The lateral medullary (Wallenberg’s) syndrome. Med Bull (Ann Arbor). 1962;28:106–13.

    CAS  Google Scholar 

  33. Currier RD, Giles CL, Dejong RN. Some comments on Wallenberg’s lateral medullary syndrome. Neurology. 1961;11:778–91.

    Article  PubMed  CAS  Google Scholar 

  34. Lister JR, Rhoton Jr AL, Matsushima T, Peace DA. Microsurgical anatomy of the posterior inferior cerebellar artery. Neurosurgery. 1982;10(2):170–99.

    Article  PubMed  CAS  Google Scholar 

  35. Chadwick GM, Asher AL, Van Der Veer CA, Pollard RJ. Adverse effects of topical papaverine on auditory nerve function. Acta Neurochir (Wien). 2008;150(9):901–9, discussion 909.

    Google Scholar 

  36. Kim B, Hwang S, Chang J, Shin W. Delayed facial palsy following microvascular decompression in hemifacial spasm. J Korean Neurosurg Soc. 1999;28:1332–6.

    CAS  Google Scholar 

  37. Kuroki A, Itagaki S, Nagai O. Delayed facial palsy after microvascular decomnpression for hemifacial spasm. Facial Nerve Res. 1991;11:147–50.

    Google Scholar 

  38. Lovely TJ, Getch CC, Jannetta PJ. Delayed facial weakness after microvascular decompression of cranial nerve VII. Surg Neurol. 1998;50(5):449–52.

    Article  PubMed  CAS  Google Scholar 

  39. Rhee DJ, Kong DS, Park K, Lee JA. Frequency and prognosis of delayed facial palsy after microvascular decompression for hemifacial spasm. Acta Neurochir (Wien). 2006;148(8):839–43, discussion 843.

    Google Scholar 

  40. Furukawa K, Sakoh M, Kumon Y, et al. [Delayed facial palsy after microvascular decompression for hemifacial spasm due to reactivation of varicella-zoster virus]. No Shinkei Geka. 2003;31(8):899–902.

    PubMed  Google Scholar 

  41. Ryu H, Yamamoto S, Miyamoto T. Atypical hemifacial spasm. Acta Neurochir (Wien). 1998;140(11):1173–6.

    Article  CAS  Google Scholar 

  42. Jannetta PJ. Surgical treatment of cranial rhizopathies. Paper presented at Congress of Neurological Surgeons, Montreal, QC, Canada; 1996.

    Google Scholar 

  43. Pollack IF, Pang D, Kocoshis S, Putnam P. Neurogenic dysphagia resulting from Chiari malformations. Neurosurgery. 1992;30(5):709–19.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Penny P. Liu .

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Sekula, R.F., Jannetta, P.J., Arnone, G.D., Liu, P.P., Liu, P.P. (2012). Surgery for Hemifacial Spasm. In: Koht, A., Sloan, T., Toleikis, J. (eds) Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0308-1_23

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  • DOI: https://doi.org/10.1007/978-1-4614-0308-1_23

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