The Fine Structure of Slow-Wave Sleep Oscillations: from Single Neurons to Large Networks

Part of the Springer Series in Computational Neuroscience book series (NEUROSCI, volume 15)


This chapter reviews experiments, analyses and models of neuronal activity in the thalamus and cerebral cortex during wake and sleep states. The emphasis is on how the microscopic (units, intracellular) and macroscopic (LFPs, EEG) activity organizes within the different states. In a first part, the correspondence between electroencephalogram (EEG) oscillations and neuronal activity is reviewed. Two types of oscillations are then examined in more detail: spindle (7–14 Hz) and slow (0.1–4 Hz) oscillations. For each, experiments and models are contrasted. Implications of these experimental and modeling results onto the role of slow-wave sleep in consolidating memories are discussed.


Slow Wave Slow Oscillation Thalamic Neuron Synaptic Interaction Natural Sleep 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Research supported by CNRS, ANR (HR-CORTEX grant), the European Community (FET grants FACETS FP6-015879, BRAINSCALES FP7-269921) and the NIH (R01EY020765).


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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Unité de Neuroscience, Information et Complexité (UNIC)CNRSGif-sur-YvetteFrance
  2. 2.Department of NeuroscienceUniversity of PennsylvaniaPhiladelphiaUSA

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