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Genetics of Age-Related Macular Degeneration

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Age-related Macular Degeneration Diagnosis and Treatment

Abstract

Age-related Macular Degeneration (AMD) is a multifactorial disease involving genetic and environmental influences. Complement Factor H (CFH) and HTRA1/LOC387715 are the two main loci associated with AMD. A genetic understanding of AMD may allow for early diagnosis and treatment.

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Authors and Affiliations

  1. Department of Ophthalmology, University of California at San Diego, Skaggs (SSPPS) Rm. 4186, 9500 Gilman Dr., La Jolla, San Diego, CA, USA

    Daniel T. Kasuga B.S.

  2. Department of Ophthalmology, University of California at San Diego, La Jolla, San Diego, CA, USA

    Yuhong Chen M.D., Ph.D.

  3. Department of Ophthalmology, Institute for Genomic Medicine, Shiley Eye Center, University of California at San Diego, La Jolla, San Diego, CA, USA

    Kang Zhang M.D., Ph.D.

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  1. Daniel T. Kasuga B.S.
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  2. Yuhong Chen M.D., Ph.D.
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  3. Kang Zhang M.D., Ph.D.
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Correspondence to Daniel T. Kasuga B.S. .

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Editors and Affiliations

  1. Wills Eye Hospital, Walnut St. 840, Philadelphia, 19107, Pennsylvania, USA

    Allen C. Ho

  2. Wills Eye Hospital, Walnut St. 840, Philadelphia, 19107, Pennsylvania, USA

    Carl D. Regillo

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Kasuga, D.T., Chen, Y., Zhang, K. (2011). Genetics of Age-Related Macular Degeneration. In: Ho, A., Regillo, C. (eds) Age-related Macular Degeneration Diagnosis and Treatment. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0125-4_1

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