Intraoperative Assessment of Donor Livers in the Transplant Setting

  • Rhonda K. YantissEmail author
Part of the Frozen Section Library book series (FROZEN)


There are two major indications for intraoperative consultation on donor liver samples during, or prior to, transplantation surgery. Surgeons may encounter unsuspected hepatic tumors during the harvest of donor organs. These lesions must be classified as benign of malignant at the time of organ harvest, since a diagnosis of primary or secondary malignancy in the liver is a contraindication to transplantation of the liver, as well as most other organs from the donor. Donor livers are also evaluated by needle biopsy prior to transplantation in order to assess for the presence and extent of macrovesicular steatosis or severity of underlying liver disease. Excessive hepatic fat is a powerful predictor of suboptimal graft function during the perioperative period.


Donor Liver Warm Ischemic Time Cold Ischemic Time Freeze Section Analysis Hepatocellular Necrosis 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineWeill Medical College of Cornell UniversityNew YorkUSA

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