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Color Atlas of Fetal and Neonatal Histology pp 251–260Cite as

Spleen

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Abstract

The histological appearance of the spleen changes dramatically during fetal life. Since much of the architecture of the spleen is not fully formed in the embryonic period, significant development of the red and white pulp occurs during the second and third trimesters of fetal life with additional changes occurring postnatally. Unfortunately, there are only a few histological studies of the human fetal spleen in the literature, and while they provide some insight into prenatal splenic development, more comprehensive analyses are needed to fully understand the changes that occur in this complex organ during fetal life.

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Author information

Authors and Affiliations

  1. Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, USA

    Linda M. Ernst MD, MHS (Assistant Professor of Pathology and Director of Perinatal Pathology)

Authors
  1. Linda M. Ernst MD, MHS
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Editor information

Editors and Affiliations

  1. Feinberg School of Medicine, Department of Pathology, Northwestern University, 710 N. Fairbanks Court, Chicago, 60611, Illinois, USA

    Linda M. Ernst

  2. Dept. Pathology, Children's Hospital Philadelphia, 324 South 34th St, Philadelphia, 19104, Pennsylvania, USA

    Eduardo D. Ruchelli

  3. Dept. Pathology, Children's Hospital Philadelphia, 324 South 34th St, Philadelphia, 19104, Pennsylvania, USA

    Dale S. Huff

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© 2011 Springer Science+Business Media, LLC

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Ernst, L.M. (2011). Spleen. In: Ernst, L., Ruchelli, E., Huff, D. (eds) Color Atlas of Fetal and Neonatal Histology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0019-6_23

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  • DOI: https://doi.org/10.1007/978-1-4614-0019-6_23

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-0018-9

  • Online ISBN: 978-1-4614-0019-6

  • eBook Packages: MedicineMedicine (R0)

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