Neurologic Manifestations of Lyme Disease

  • John J. Halperin
Part of the Clinical Topics in Infectious Disease book series (CLIN.TOP.INFECT)


The identification of Borrelia burgdorferi as the tick-borne pathogen responsible for Lyme disease1–3 has rekindled interest in spirochetal diseases of the nervous system for the first time since penicillin threatened to relegate neurosyphilis to obscurity. Anecdotal reports have suggested that this novel organism might be responsible for neurologic disorders affecting the cerebral cortex, skeletal muscle, and all points in between. Reports in the lay press have implied that this is a health menace of plaguelike proportions. However, the true spectrum of problems caused by this infection remains to be defined.


Amyotrophic Lateral Sclerosis Cranial Nerve Lyme Disease Optic Neuritis Central Nervous System Infection 
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© Springer-Verlag New York Inc. 1990

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  • John J. Halperin

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