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AIDS and Other Immunocompromised States

  • Chapter
Infections of the Nervous System

Part of the book series: Clinical Topics in Infectious Disease ((CLIN.TOP.INFECT))

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Abstract

Alterations in host defense mechanisms that predispose to infection can be broadly classified into three major categories: abnormalities of cell-mediated immunity (T-lymphocytes and macrophages), abnormalities of humoral immunity (immunoglobulins), and abnormal neutrophils. Currently, the most common cause of abnormalities in the cell-mediated arm of immunity is the acquired immunodeficiency syndrome (AIDS), but among other causes, abnormalities in this system are also associated with lymphoma, particularly Hodgkin’s disease, corticosteroid and antineoplastic therapy, organ transplantation, and malnutrition.

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References

  1. Gallo RC, Salahuddin SZ, Popovic M, et al: Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. Science 1984; 224: 500–503.

    Article  PubMed  CAS  Google Scholar 

  2. Johnson RT, McArthur JC, Narayan 0: The neurology of human immunodeficiency virus infections. FASEB J 1988; 2: 2970–2981.

    PubMed  CAS  Google Scholar 

  3. Gallo RC, Kalyanaraman VS, Sarngadharan MG, et al: Assoccation of the human type-C retrovirus with a subset of adult T-cell cancers. Cancer Res 1983; 43: 3892–3899.

    PubMed  CAS  Google Scholar 

  4. deThe G: HTLV-I and chronic progressive encephalomyelopathies: an immunolovirological perspective, in Roman GC, Vernant J-C, Osame M (eds): HTLV-1 and the Nervous System. New York, Alan R. Liss, 1989, pp 3–8.

    Google Scholar 

  5. Gottlieb MS, Schroff R, Schranker HM, et al: Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men. N Engl J Med 1981; 305: 1425–1431.

    Article  PubMed  CAS  Google Scholar 

  6. Masur H, Michelis MA, Greene JB, et al: An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction. N Engl J Med 1981; 305: 1431–1438.

    Article  PubMed  CAS  Google Scholar 

  7. Siegal FP, Lopez C, Hammer GS, et al: Severe acquired immunodeficiency in male homosexuals manifested by chronic perianal ulcerative Herpes simplex lesions. N Engl J Med 1981; 305: 1439–1444.

    Article  PubMed  CAS  Google Scholar 

  8. Snider WD, Simpson DM, Nielsen S, et al: Neurological complications of the acquired immunodeficiency syndrome: analysis of 50 patients. Ann Neurol 1983; 14: 403–418.

    Article  PubMed  CAS  Google Scholar 

  9. Levy RM, Bredesen DE, Rosenblum ML: Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature. J Neurosurg 1985; 62: 475–495.

    Article  PubMed  CAS  Google Scholar 

  10. Berger JR, Moskowitz L, Fischl M, Kelley RE: Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome. South Med J 1987; 80: 683–686.

    Article  PubMed  CAS  Google Scholar 

  11. Bredesen DE, Messing R: Neurological syndromes heralding the acquired immunodeficiency syndrome (abstract). Ann Neurol 1983; 14: 141.

    Google Scholar 

  12. Gray F, Gherardi R, Scaravilli F: The neuropathology of the acquired immune deficiency syndrome (AIDS). Brain 1988; 111: 245–266.

    Article  PubMed  Google Scholar 

  13. Rhodes R: Histopathology of the central nervous system in the acquired immunodeficiency syndrome. Hum Pathol 1987; 18: 636–643.

    Article  PubMed  CAS  Google Scholar 

  14. Ho DD, Bredesen DE, Vinters, Daar ES: The acquired immunodeficiency syndrome (AIDS) dementia complex. Ann Intern Med 1989; 111: 400–410.

    PubMed  CAS  Google Scholar 

  15. Nielsen SL, Petito CK, Urmacher CS, Posner JB: Subacute encephalitis in acquired immune deficiency syndrome: a postmortem study. Am J Clin Pathol 1984; 82: 678–682.

    PubMed  CAS  Google Scholar 

  16. Moskowitz LB, Hensley GT, Chan JC, et al: The neuropathology of acquired immunodeficiency syndrome. Arch Pathol Lab Med 1984; 108: 867–872.

    PubMed  CAS  Google Scholar 

  17. Kato T, Hirano A, Llena JF, Dembitzer HM: Neuropathology of acquired immune deficiency syndrome (AIDS) in 53 autopsy cases with particular emphasis on microglial nodules and multinucleated giant cells. Acta Neuropathol (Berl) 1987; 73: 287–294.

    Article  CAS  Google Scholar 

  18. Levy JA, Shimabukuro J, Hollander H, et al: Isolation of AIDS assocated retroviruses from cerebrospinal fluid and brain of patients with neurological symptoms. Lancet 1985; 2: 586–588.

    PubMed  CAS  Google Scholar 

  19. Ho DD, Rota TR, Schooley RT, et al: Isolation of HTLV-III from cerebrospinal fluid and neural N Engl J Med 1985; 313: 1493–1497.

    Article  PubMed  CAS  Google Scholar 

  20. De la Monte SM, Moore T, Hedley-Whyte ET: Vacuolar encephalopathy of AIDS (letter). N Engl J Med 1986; 315: 1549–1550.

    PubMed  Google Scholar 

  21. Epstein LG, Sharer LR, Cho E-S, et al: HTLV-III/ LAV-like retrovirus particles in the brains of patients with AIDS encephalopathy. AIDS Res 1985; 1: 447–454.

    Article  CAS  Google Scholar 

  22. Shaw GM, Harper ME, Hahn BH, et al: HTLV-III infection in brains of children and adults with AIDS encephalopathy. Science 1985; 227: 177–182.

    Article  PubMed  CAS  Google Scholar 

  23. Resnick L, Berger JR, Shapshak P. Tourtellotte WW: Early penetration of the blood-brain-barrier by HIV. Neurology 1988; 38: 9–14.

    PubMed  CAS  Google Scholar 

  24. Gajdusek DC, Amyx HL, Gibbs CJ, et al: Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patients. Lancet 1985; 1: 55–56.

    Article  PubMed  CAS  Google Scholar 

  25. Cheng-Mayer C, Rutka JK, Rosenblum ML, et al: HIV can productively infect cultured human glial cells. PNAS (USA) 1987; 84: 3526–3530.

    Article  CAS  Google Scholar 

  26. Gonda MA, Wong-Stall F, Gallo RV, et al: Sequence homology and morphologic similarity of HITLV-III and visna virus, a pathogenic lentivirus. Science 1985; 227: 173–177.

    Article  PubMed  CAS  Google Scholar 

  27. Ho DD, Sarngadharan MG, Resnick L, et al: Primary human T-lymphotropic virus type III infection. Ann Intern Med 1985; 103: 880–883.

    PubMed  CAS  Google Scholar 

  28. Cooper DA, Gold J, Maclean P, et al: Acute AIDS retrovirus infection: definition of a clinical illness associated with seroconversion. Lancet 1985; 1: 537–540.

    Article  PubMed  CAS  Google Scholar 

  29. Ranki A, Vallf SL, Krohn M, et al: Long latency precedes overt seroconversion in sexually transmitted immunodeficiency-virus infection. Lancet 1987; 2: 589–593.

    Article  PubMed  CAS  Google Scholar 

  30. Imagawa DT, Lee MH, Wolinsky SM, et al: Human immunodeficiency virus type 1 infection in homosexual men who remain seronegative for prolonged periods. N Engl J Med 1989; 320: 1458–1462.

    Article  PubMed  CAS  Google Scholar 

  31. Goudsmit J, Lange JM, Krone WJ, et al: Pathogenesis of HIV and its implications for serodiagnosis and monitoring of antiviral therapy. J Virol Meth 1987; 17: 19–34.

    Article  CAS  Google Scholar 

  32. Wolinsky S, Rinaldo C, Farzedegan H, et al: Polymerase chain reaction (PCR) detection of HIV provirus before HIV seroconversion. Presented at the Fourth International Conference on AIDS. Stockholm, June 12–16, 1988.

    Google Scholar 

  33. Hollander H, Stringari S: Human immunodeficiency virus-associated meningitis. Clinical course and correlations. Am J Med 1987; 83: 813–816.

    Article  PubMed  CAS  Google Scholar 

  34. Carne CA, Tedder RS, Smith A, et al: Acute encephalopathy coincident with seroconversion for anti-HTLV-III. Lancet 1985; 1206–1208.

    Google Scholar 

  35. Denning DW, Anderson J, Rudge P, Smith H: Acute myelopathy associated with primary infection with human immunodeficiency virus. Br Med J (Clin Res) 1987; 294: 143–144.

    Article  CAS  Google Scholar 

  36. Calabrese LH, Profitt MR, Levin KH, et al: Acute infection with human immunodeficiency virus (HIV) associated with acute brachial neuritis and exanthematous rash. Ann Intern Med 1987; 107: 849–851.

    PubMed  CAS  Google Scholar 

  37. Elovaara I, livanainen M, Valle SL, et al: CSF protein and cellular profiles in various stages of HIV infection related to neurological manifestations. J Neurol Sci 1987; 78: 331–342.

    Article  PubMed  CAS  Google Scholar 

  38. Marshall DW, Brey RL, Cahill WT, et al: Spectrum of cerebrospinal fluid findings in various stages of human immunodeficiency virus infection. Arch Neurol 1988; 45: 954–958.

    Article  PubMed  CAS  Google Scholar 

  39. Britton CB, Miller JR: Neurologic complications in acquired immunodeficiency syndrome. Neurol Clin 1984; 2: 315–339.

    PubMed  CAS  Google Scholar 

  40. Navia BA, Price RW: AIDS dementia complex as the presenting or sole manifestation of HIV infection. Arch Neurol 1987; 44: 65–72.

    Article  PubMed  CAS  Google Scholar 

  41. Navia BA, Price RW: AIDS dementia complex: Ann Neurol 1986; 19: 525–535.

    Article  PubMed  CAS  Google Scholar 

  42. Berger JR, Fischl M, Resnick L, et al: Evidence of human immunodeficiency virus encephalopathy in the absence of overt neurological disease (abstract). Proc Int Conf AIDS 1987; 3: 85.

    Google Scholar 

  43. Grant I, Atkinson JH, Hesselink JR, et al: Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infections: studies with neuropsychologic testing and magnetic resonance imaging. Ann Intern Med 1987; 107: 828–836.

    PubMed  CAS  Google Scholar 

  44. Wilkie FL, Eisdorfer C, Morgan R, et al: Cognition in early HIV infection. Arch Neurol 1990; 47: 433–440.

    Article  PubMed  CAS  Google Scholar 

  45. Stern Y, Sano M, Goldtein S, et al: Neuropsychological manifestations of HIV infection in gay men (abstract). Fifth International Conference on AIDS, Montreal, 1988, p 383.

    Google Scholar 

  46. Clifford D, Miller JP, Deyfried E, et al: Neuropsychometric function in early HIV positive patients compared with a matched HIV negative population. Fifth International Conference on AIDS, Montreal, 1988, p 460.

    Google Scholar 

  47. Woo S, Hunter J, Wang P, et al: A brief screening test battery for cognitive deficits in HIV infection (abstract). Fifth International Conference on AIDS, Montreal, 1988, p 384.

    Google Scholar 

  48. Becky-Barr D, Perry S, Swanda R, et al: Neuropsychological function in physically asymptomatic HIV seropositive and seronegative gay/bisexual men (abstract). Fifth International Conference on AIDS, Montreal, 1988, p 381.

    Google Scholar 

  49. Perdices M, Cooper DA: Simple and choice reaction time in patients with human immunodeficiency virus infection. Ann Neurol 1989; 25: 460–467.

    Article  PubMed  CAS  Google Scholar 

  50. De la Monte SM, Ho DD, Schooley RT, et al: Subacute encephalomyelitis of AIDS and its relation to HTLV-III infection. Neurology 1987; 37: 562–569.

    Google Scholar 

  51. Price RW, Brew B, Sidtis J, et al: The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 1988; 239: 586–592.

    Article  PubMed  CAS  Google Scholar 

  52. Tross S, Price RW, Navia B, et al: Neuropsychological characterization of the AIDS dementia complex: a preliminary report. AIDS 1988; 2: 81–88.

    Article  PubMed  CAS  Google Scholar 

  53. Sidtis J, Amitai H, Ornitz D, Price RW: The brief neuropsychological examination for AIDS dementia complex correlations with functional status scales and other neuropsychological tests. Proceedings of Third Interational Conference on AIDS, Washington, DC, June 1987, p 55.

    Google Scholar 

  54. Beckett A, Manschreck T, Vitagliano H, et al: Symptomatic HIV infection of the CNS in a patient without clinical evidence of immune deficiency. Am J Psychiatry 1987; 44: 1342–1344.

    Google Scholar 

  55. Navia BA, Price RW: The acquired immunodeficiency syndrome dementia complex as the presenting or sole manifestation of human immunodeficiency virus infection. Arch Neurol 1987; 44: 64–69.

    Article  Google Scholar 

  56. Faulstich ME: Acquired immune deficiency syndrome: an overview of central nervous system complications and neuropsychological sequelae. Int J Neurosci 1986; 30: 249–254.

    Article  PubMed  CAS  Google Scholar 

  57. Commings MA, Cummings KL, Rapaport MH, et al: Acquired immunodeficiency syndrome presenting as schizophrenia. West J Med 1987; 146: 615–618.

    Google Scholar 

  58. Nurnberg HG, Prudic J, Fiori M, et al: Psychopathology complicating acquired immune deficiency syndrome (AIDS). Am J Psychiatry 1985; 141: 95–96.

    Google Scholar 

  59. Thomas CS, Toone BK, El Komy A, et al: HTLV III and psychiatric disturbance (letter). Lancet 1985; 1: 395–396.

    Article  Google Scholar 

  60. Kermani EJ, Borod JC, Brown P, et al: New psychopathologic findings in AIDS: case report. J Clin Psychiatry 1985; 46: 240–241.

    PubMed  CAS  Google Scholar 

  61. Beckett A, Summergrad P, Manschreck T, et al: Symptomatic HIV infection of the CNS in a patient without clinical evidence of immune deficiency. Am J Psychiatry 1987; 144: 1342–1344.

    PubMed  CAS  Google Scholar 

  62. Kermani E, Drob S, Alpert M: Organic brain syndrome in three cases of acquired immune deficiency syndrome. Compr Psychiatry 1984; 25: 294–297.

    Article  PubMed  CAS  Google Scholar 

  63. McHugh PR, Folstein MF: Psychiatric syndromes of Huntingtons chorea: a clinical and phenomenologic study, in Benson F, Blumer D (eds): Psychiatric Aspects of Neurological Disease. New York, Grune and Stratton, 1975.

    Google Scholar 

  64. Hollander H, Golden J, Mendelson T, et al: Extrapyramidal symptoms in AIDS patients given low-dose metoclopropamide or chlorpromazine (letter). Lancet 1985; 2: 11–86.

    Google Scholar 

  65. Edelstein H, Knight RT: Severe parkinsonism in two AIDS patients taking prochlorperazine (letter). Lancet 1987; 2: 341–342.

    Article  PubMed  CAS  Google Scholar 

  66. Metzer WS: Movement disorders with AIDS encephalopathy: case report. Neurology 1987; 37: 1438.

    PubMed  CAS  Google Scholar 

  67. Currie J, Benson E, Ramsden B, et al: Eye movement abnormalities as a predictor of the acquired immunodeficiency syndrome dementia complex. Arch Neurol 1988; 45: 949–953.

    Article  PubMed  CAS  Google Scholar 

  68. Tervo T, Elovaara H, Karli SL, et al: Ocular motility abnormalities as an early sign of CNS involvement in HIV infection (letter). Lancet 1986; 2: 512.

    Article  PubMed  CAS  Google Scholar 

  69. Navia BA, Jordan BD, Price RW: The AIDS dementia complex: I Clinical features. Ann Neurol 1986; 19: 517–524.

    Article  PubMed  CAS  Google Scholar 

  70. Epstein LG, Sharer LR, Joshi VV, et al: Progressive encephalopathy in children with acquired immune deficiency syndrome. Ann Neurol 1985; 17: 488–496.

    Article  PubMed  CAS  Google Scholar 

  71. Belman AL, Ultmann MH, Horoupian D, et al: Neurological complications in infants and children with acquired immune deficiency syndrome Ann Neurol 1985; 18: 560–566.

    Article  PubMed  CAS  Google Scholar 

  72. Davis SL, Halsted CC, Levy N, Ellis W: Acquired immune deficiency syndrome presenting as progressive infantile encephalopathy. J Pediatr 1987; 110: 884–888.

    Article  PubMed  CAS  Google Scholar 

  73. Ragni MV, Urbach AH, Taylor S, et al: Isolation of human immunodeficiency virus and detection deficiency syndrome and progressive encephalopathy. J Pediatr 1987; 110: 892–894.

    Article  PubMed  CAS  Google Scholar 

  74. Epstein LG, Sharer LR, Oleske JM, et al: Neurologic manifestations of human immunodeficiency virus infection in children. Pediatrics 1986; 78: 678–687.

    PubMed  CAS  Google Scholar 

  75. Ultmann MH, Belman AL, Ruff HA, et al: Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex. Dey Med Child Neurol 1985; 27: 563–571.

    Article  CAS  Google Scholar 

  76. Vinters HV: The AIDS dementia complex (letter). Ann Neurol 1987; 21: 612.

    Article  PubMed  CAS  Google Scholar 

  77. Anders KH, Guerra WF, Tomiyasu U, et al: The neuropathology of AIDS, UCLA experience and review. Am J Pathol 1986; 124: 537–558.

    PubMed  CAS  Google Scholar 

  78. Anders K, Steinsapir KD, Iverson DJ, et al: Neuropathologic findings in the acquired immunodeficiency syndrome (AIDS) Clin Neuropathol 1986; 5: 120.

    Google Scholar 

  79. Popovic M, Sarngadharan MG, Read E, Gallo RC: Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984; 224: 497–500.

    Article  PubMed  CAS  Google Scholar 

  80. Schwenk J, Cruz-Sanchez F, Gosztonyi G, CervosNavarro J: Spongiform encephalopathy in a patient with the acquired immune deficiency syndrome (AIDS). Acta Neuropathol 1987; 74: 389–392.

    Article  PubMed  CAS  Google Scholar 

  81. Sharer LR, Epstein LG, Cho E-S, et al: Pathologic features of AIDS encephalopathy in children: evidence for LAV/HTLV-III infection of brain. Hum Pathol 1986; 17: 271–284.

    Article  PubMed  CAS  Google Scholar 

  82. Belman AL, Lantos G, Horoupian D, et al: AIDS: Calcification of the basal ganglia in infants and children. Neurology 1986; 36: 1192–1199.

    PubMed  CAS  Google Scholar 

  83. Wiley CA, Schrier RD, Nelson JA, et al: Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency patients. Proc Nall Acad Sci 1986; 83: 7089–7093.

    Article  CAS  Google Scholar 

  84. Stoler MH, Eskin TA, Benn S, et al: Human T-cell lymphotropic virus type III infection of the central nervous system-a preliminary in situ analysis. JAMA 1986; 256: 2360–2364.

    Article  PubMed  CAS  Google Scholar 

  85. Pumarola-Sune T, Navia BA, Cardon-Cardo C, et al: HIV antigen in the brains of patients with AIDS dementia complex. Ann Neurol 1987; 21: 490–496.

    Article  PubMed  CAS  Google Scholar 

  86. Gabuzda DH, Ho DD,, de la Monte SM et al: Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol 1986; 20: 289–295.

    Article  PubMed  CAS  Google Scholar 

  87. Hill JM, Farrar WL, Pert CB: Localization of the T4 antigen/AIDS virus receptor in monkey and rat brain: prominence in cortical regions. Psychopharmacol Bull 1986; 22: 689–694.

    PubMed  CAS  Google Scholar 

  88. Fauci AS: The immunopathogenesis of AIDS, in Gottlieb MS, et al (eds): Current Topics in AIDS, Vol 1. New York, Wiley, 1987, pp 119–232.

    Google Scholar 

  89. Moargolick JB, Lane HC, Fauci AS: Immunopathogenesis of HTLV-III/LAV infection, in Gallo RC, Haseltine W, Klein G, zur Hausen H, (eds): Viruses and Brain Cancer, Vol 1. New York, Alan Liss, 1987, pp 59–79.

    Google Scholar 

  90. Funke I, Hahn A, Rieber EP, et al: The cellular receptor (CD 4) of the human immunodeficiency virus is expressed on neurons and glial cells of human brain. J Exp Med 1987; 165: 1230–1235.

    Article  PubMed  CAS  Google Scholar 

  91. Koenig S, Gendelman HE, Orenstein JM, et al: Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 1986; 233: 1089–1093.

    Article  PubMed  CAS  Google Scholar 

  92. Gartner S, Markovits P, Markovits DM, et al: Virus isolation from and identification of HTLV-IIULAVproducing cells in brain tissue from a patient with AIDS. JAMA 1986; 256: 2365–2371.

    Article  PubMed  CAS  Google Scholar 

  93. Gabuzda DH, Ho DD,, de la Monte SM et al: Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol 1986; 20: 289–295.

    Article  PubMed  CAS  Google Scholar 

  94. Koyanagi Y, Miles S, Mitsuyasu RT, et al: Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 1987; 236: 819–822.

    Article  PubMed  CAS  Google Scholar 

  95. Anand R, Siegal F, Reed C, et al: Non-cytocidal natural variants of human immunodeficiency virus isolated from AIDS patients with neurological disorders. Lancet 1987; 2: 234–238.

    Article  PubMed  CAS  Google Scholar 

  96. Cheng-Mayer C, Levy JA: Distinct biological and serological properties of human immunodeficiency viruses from the brain. Ann Neurol 1988; 23 (suppl): 58–61.

    Article  Google Scholar 

  97. Von Briesen H, Becker WB, Henco K, et al: Isolation frequency and growth properties of HIV-variants: multiple simultaneous variants in a patient demonstrated by molecular cloning. J Med Virol 1987; 23: 51–66.

    Article  Google Scholar 

  98. Yarchoan R, Weinhold KJ, Lyerly HK, et al: Administration of 3’ -azido-3’ -deoxythymidine, and inhibitor of HTLV III/LAV replication, to patients with AIDS or AIDS-related complex. Lancet 1986; 1: 570–580.

    Google Scholar 

  99. McDonald EM, Mann AH, Thomas HC: Interferons as mediators of psychiatric morbidity. Lancet 1987; 2: 1175–1178.

    Article  PubMed  CAS  Google Scholar 

  100. Kumar M, Resnick L, Berger JR, et al: AIDS dementia complex associated with brain reactive antibodies. J AIDS 1989; 2: 469–471.

    CAS  Google Scholar 

  101. Pert CB, Hill JH, Ruff MR, et al: Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibits human immunodeficiency virus receptor binding and T-cell infectivity. Proc Nall Acad Sci USA 1986; 83: 92549258.

    Google Scholar 

  102. Sacerdote P, Ruff MR, Pert CB: Vasocactive intestinal peptide 1–12: a ligand for the CD4 (T4) human immunodeficiency virus receptor. J Neurosci Res 1987; 18: 102–107.

    Article  PubMed  CAS  Google Scholar 

  103. Lee MR, Ho DD, Gurney ME. Functional interaction and partial homology between human immunodeficiency virus and neuroleukin. Science 1987; 237: 1047–1051.

    Article  PubMed  CAS  Google Scholar 

  104. Michaels J, Sharer LR, Epstein LG: Human immunodeficiency virus type 1 (HIV-1) infection of the nervous system: a review. Immunodeficiency Rev 1988; 1: 71–104.

    CAS  Google Scholar 

  105. Rottenberg DA, Moeller JR, Strother SC, et al: The metabolic pathology of the AIDS dementia complex. Ann Neurol 1987; 22: 700–706.

    Article  PubMed  CAS  Google Scholar 

  106. Moeller JR, Strother SC, Sidtis JJ, Rottenberg DA: The scaled subprofile model: a statistical approach to the analysis of functional patterns in positron emission tomographic data. J Cereb Blood Flow Metab 1987; 7: 649–658.

    Article  PubMed  CAS  Google Scholar 

  107. Ell PJ, Costa DC, Harrison M: Imaging cerebral damage in HIV infection. Lancet 1987; 2: 569–570.

    Article  PubMed  CAS  Google Scholar 

  108. Brun B, Boesen F, Gerstoft J, et al: Crebral computed tomography in men with acquired immunodeficiency syndrome. Acta Radiol Diagn 1986; 27: 385–387.

    CAS  Google Scholar 

  109. Brun B, Boesen F, Gerstoft J, et al: Crebral computed tomography in men with acquired immunodeficiency syndrome. Acta Radiol Diagn 1986; 27: 385–387.

    CAS  Google Scholar 

  110. Post MJD, Berger JR, Hensley GT: The radiology of central nervous system disease in acquired immunodeficiency syndrome, in Taveras JM, Ferrucci JT (eds): Radiology: Diagnosis-Imaging-Intervention. Philadelphia, J.B. Lippincott, 1988, pp 1–26.

    Google Scholar 

  111. Olesen WL, Longo FM, Mills CM, Norman D: White matter disease in AIDS: findings at MR imaging. Radiology 1988; 169: 445–448.

    Google Scholar 

  112. Post MJD, Sheldon JJ, Hensley GT, et al: Central nervous system disease in acquired immunodeficiency syndrome: prospective correlation using CT, MR imaging and pathologic studies. Radiology 1986; 158: 141–148.

    PubMed  CAS  Google Scholar 

  113. Price RW, Navia BA: Infections in AIDS and in other immunosuppressed patients, in Kennedy PGE, Johnson RT (eds). Infections of the Nervous System, London, Butterworth, 1987, pp 248–273.

    Google Scholar 

  114. Schmitt FA, Bigley JW, McKinnis R, et al: Neuropsychological outcome of zidovudine (AZT) treatment of patients with AIDS and AIDS-related complex. N Engl J Med 1988; 319: 1573–1578.

    Article  PubMed  CAS  Google Scholar 

  115. Pizzo PA, Eddy J, Falloon J, et al: Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection. N Engl J Med 1988; 319: 889–896.

    Article  PubMed  CAS  Google Scholar 

  116. Petito CK, Navia BA, Cho ES, et al: Vacuolar myelopathy pathologically resembling subacute combined degeneration in patients with the acquired immunodeficiency syndrome. N Engl J Med 1985; 312: 874–879.

    Article  PubMed  CAS  Google Scholar 

  117. Goldstick L, Mandybur TI, Bode R: Spinal cord degeneration in AIDS. Neurology 1985; 35: 103.

    PubMed  CAS  Google Scholar 

  118. Helweg-Larsen S, Jakobsen J, Boesen F, et al: Myelopathy in AIDS. A clinical and electrophysiological study of 23 Danish patients. Acta Neurol Scand 1988; 77: 64–73.

    Article  PubMed  CAS  Google Scholar 

  119. Honig LS, Vogel H, Horoupian DS: Chronic myelopathy as a presenting symptom in HIV infection (abstract). Neurology I989;39(suppl 1 ): 419.

    Google Scholar 

  120. Signh BM, Levine S, Yarrish RL, et al: Spinal cord syndromes in the acquired immune deficiency syndrome. Acta Neurol Scand 1986; 73: 590–598.

    Article  Google Scholar 

  121. Dickson DW, Belman AL, Km TS, et al: Spinal cord pathology in pediatric acquired immunodeficiency syndrome. Neurology 1989; 39: 227–235.

    PubMed  CAS  Google Scholar 

  122. Denning DW, Anderson J, Rudge P, Smith H: Acute myelopathy associated with primary infection with human immunodeficiency virus. Br Med J 1987; 294: 143–144.

    Article  CAS  Google Scholar 

  123. Tucker T, Dix RD, Katzen C, et al: Cytomegalovirus and herpes simplex virus ascending myelitis in a patient with acquired immune deficiency syndrome. Ann Neurol 1985; 18: 74–79.

    Article  PubMed  CAS  Google Scholar 

  124. Britton CB, Mesa-Tejada R, Fenoglio CM, et al: A new complication of AIDS: thoracic myelitis caused by herpes simplex virus. Neurology 1985; 35: 1071 1074.

    Google Scholar 

  125. McArthur JC: Neurologic manifestations of AIDS. Medicine 1987; 66: 407–437.

    Article  PubMed  CAS  Google Scholar 

  126. McArthur JC, Griffin JW, Comblath DR, Farzadegan H: Progressive HTLV-1-associated myeloneuropathy in a patient with HIV-1 (abstract). Neurology 1989; 39 (suppl 1): 419.

    Google Scholar 

  127. Woolsey RM, Chanmbers TJ, Chung HK, McGarry JD: Mycobacterial meningomyelitis associated with human immunodeficiency virus infection. Arch Neurol 1988; 45: 691–693.

    Article  PubMed  CAS  Google Scholar 

  128. Doll DC, Yarbro JW, Phillips K, Klott C: Mycobacterial spinal cord abscess with an ascending polyneuropathy (letter). Ann Intern Med 1987; 106: 333–334.

    PubMed  CAS  Google Scholar 

  129. Jordan BD, Navia BA, Petito C, et al: Neurological syndromes complicating AIDS. Front Radiat Ther Oncol 1985; 19: 82–87.

    PubMed  CAS  Google Scholar 

  130. Weill O, Finaud M, Bille F, et al: Gliome malin medullaire: une nouvelle complication de l’infection par le HIV? (letter). Presse Med 1987; 16: 1977.

    PubMed  CAS  Google Scholar 

  131. Berger JR, Sheremata WA, Resnick L, et al: Multiple sclerosis-like illness occurring with human immunodeficiency virus infection. Neurology 1989; 39: 324–328.

    PubMed  CAS  Google Scholar 

  132. Janssen RS, Saykin AJ, Kaplan JE, et al: Neurological complications of human immunodeficiency virus infection in patients with lymphadenopathy syndrome. Ann Neurol 1988; 23: 49–55.

    Article  PubMed  CAS  Google Scholar 

  133. Miller RG, Kiprov DD, Parry G, Bredesen DE: Peripheral nervous system dysfunction in acquired immunodeficiency syndrome, in Rosenblum ML, Levy RM, Bredesen DE (eds): Aids and the Nervous System. New York, Raven Press, 1988, pp 65–78.

    Google Scholar 

  134. Lipkin WI, Parry G, Kiprov D, et al: Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology 1985; 35: 1479–1483.

    PubMed  CAS  Google Scholar 

  135. Rance NE, McArthur JC, Cornblath DR, et al: Gracile tract degeneration in patients with sensory neuropathy and AIDS. Neurology 1988; 38: 265–271.

    PubMed  CAS  Google Scholar 

  136. Miller RG, Parry G, Lang W, et al: AIDS-related inflammatory polyradiculopathy: prediction of response to plasma exchange with electrophysiologic testing. Muscle Nerve 1985; 8: 626.

    Article  Google Scholar 

  137. Cornblath DR, McArthur JC, Kennedy PGE, et al: Inflammatory demyelinating peripheral neuropathies associated with human T-cell lymphotropic virus type III infection. Ann Neurol 1987; 21: 32–40.

    Article  PubMed  CAS  Google Scholar 

  138. Mishra BB, Sommers W, Koski CK, Greenstein JI: Acute inflammatory demyelinatig polyneuropathy in the acquired immune deficiency syndrome. Ann Neurol 1985; 131–132.

    Google Scholar 

  139. Berger JR, Difini JA, Swerdloff MA, Ayyar DR: HIV seropositivity in Guillain-Barré syndrome (letter). Ann Neurol 1987; 22: 393–394.

    Article  PubMed  CAS  Google Scholar 

  140. Cornblath DR, McArthur JC, Griffin JW: The spectrum of peripheral neuropathies in HTLV-III infection. Muscle Nerve 1986; 9: 76.

    Article  Google Scholar 

  141. Dalakas MC: Neuromuscular complications of AIDS. Muscle Nerve 1986; 9: 92.

    Google Scholar 

  142. Stricker RB, Bredesen DE, Wesley AM, et al: Auto-antibodies in HIV-related peripheral neuropathy. Presented at the Neurological and Neuropsychological Complications of HIV Infection Satellite Symposia to the Fifth International Conference on AIDS, Quebec City, 1989, p 30.

    Google Scholar 

  143. Eidelberg D, Sotrel A, Vogel H, et al: Progressive polyradiculopathy in acquired immunie deficiency syndrome. Neurology 1986; 36: 912–916.

    PubMed  CAS  Google Scholar 

  144. Parry GJ: Peripheral neuropathies associated with human immunodeficiency virus infection. Ann Neurol 1988;23(suppl): S49-S 53.

    Google Scholar 

  145. Elder G, Dalakas M, Pezeshkpour G, et al: Ataxic neuropathy due to ganglioneuritis after probable acute human immunodeficiency virus infection. Lancet 1986;ii:1275–1276.

    Google Scholar 

  146. Pialoux G, Dupont B, Sansonetti P, et al: Polyradiculonevrite des nerfs craniens au cous du syndrome d’immunodeficit acquis. Pressè Med 1987; 16: 967.

    PubMed  CAS  Google Scholar 

  147. Brown MA, Thompson A, Goh BT, et al: Bell’s palsy and HIV infection. J Neurol Neurosurg Psychiatry 1988; 51: 42–426.

    Google Scholar 

  148. Cole EL, Meisler DM, Calabrese LH, et al: Herpes zoster ophthalmicus and acquired immune deficiency syndrome. Arch Ophthalmol 1984; 102: 1027.

    Article  PubMed  CAS  Google Scholar 

  149. Cole EL, Meisler DM, Calabrese LH, et al: Herpes zoster ophthalmicus and acquired immune deficiency syndrome. Arch Ophthalmol 1984; 102: 1027.

    Article  PubMed  CAS  Google Scholar 

  150. Lanska MJ, Lanska DJ, Schmidley JW: Syphilitic polyradiculopathy in an HIV-positive man. Neurology 1988; 38: 1297–1301.

    PubMed  CAS  Google Scholar 

  151. Zochodne DW, Bolton CF, Wells GA, et al: Critical illness polyneuropathy: a complication of sepsis and multiple organ failure. Brain 1987; 110: 819–842.

    Article  PubMed  Google Scholar 

  152. Dalakas MC, Pezeshkpour GH, Gravel(M, et al: Polymyositis associated with AIDS retrovirus. JAMA 1986; 256: 2381–2383.

    Article  PubMed  CAS  Google Scholar 

  153. Bailey RO, Turok DI, Jaufman BP, Singh JK: Myositis and acquired immunodeficiency syndrome. Hum Pathol 1987; 18: 749–751.

    Article  PubMed  CAS  Google Scholar 

  154. Dalakas MC, London WT, Gravel(M, et al: Polymyositis in an immunodeficiency disease in monkeys induced by a type D retrovirus. Neurology 1986; 36: 569–572.

    PubMed  CAS  Google Scholar 

  155. Dalakas MC, Gravel(M, London WT, et al: Morphological changes of an inflammatory myopathy in rhesus monkeys with simian acquired immunodeficiency syndrome. Proc Soc Exp Biol Med 1987; 185: 368–376.

    PubMed  CAS  Google Scholar 

  156. Bessen LJ, Greene JB, Louie E: Severe polymyositis-like syndrome associated with zidovudinee therapy of AIDS and ARC (letter). N Engl J Med 1988; 318: 708.

    PubMed  CAS  Google Scholar 

  157. Simpson D, Wolfe D, Farraye J, Bender A: HIV associated myopathy: features in 21 patients and role of AZT (abstract). Fifth International Conference on AIDS, Montreal, 1989, p 276.

    Google Scholar 

  158. Dalakas M, Peseahkpoor GH, Illa I, Nath A: Destructive inflammatory myopathy with abnormal mitochondria (DIM-Mi) in nine HIV-positive patients treated with zidovudine. Presented at the Neurological and Neuropsychological Complications of HIV Satellite Symposium to the Fifth International Conference on AIDS, Quebec City, 1989, p 120.

    Google Scholar 

  159. Dalakas MC, Pezeshkpour GH, Flaherty M: Progressive nemaline (rod) myopathy associated with HIV infection (letter). N Engl J Med 1987; 317: 1602–1603.

    Article  PubMed  CAS  Google Scholar 

  160. Watts RA, Hoffbrand BI, Paton DF, Davis JC: Pyomyositis associated with human immunodeficiency virus infection. Br Med J 1987; 294: 1524–1525.

    Article  CAS  Google Scholar 

  161. Uldry PA, Steck Ai, Regli F: Paralysis of the trapezius muscle in HIV infection (letter). Presse Med 1987; 16: 1654.

    PubMed  CAS  Google Scholar 

  162. Drane WE, Tipler BM: Heterotopic ossification (myositis ossificans) in acquired immunodeficiency syndrome. Detection by gallium scintigraphy. Clin Nucl Med 1987; 12: 433–435.

    Article  PubMed  CAS  Google Scholar 

  163. Drew WL: Cytomegalovirus infection in patients with AIDS. J Infect Dis 1988; 158: 449–456.

    Article  PubMed  CAS  Google Scholar 

  164. Huang ES, Alford CA, Reynolds DW, et al: Molecular epidemiology of cytomegalovirus infections in women and their infants. N Engl J Med 1980; 303: 958–962.

    Article  PubMed  CAS  Google Scholar 

  165. Hutto C, Ricks R, Garvie M, et al: Epidemiology of cytomegalovirus infections in young children: day care vs. home care. Pediatr Infect Dis 1985; 4: 149–152.

    Article  PubMed  CAS  Google Scholar 

  166. Spector SA, Hirata KK, Neuman TR: Identification of multiple cytomegalovirus strains in homosexual men with acquired immunodeficiency syndrome. J Infect Dis 1984; 150: 953–956.

    Article  PubMed  CAS  Google Scholar 

  167. Bale JF Jr: Human cytomegalovirus infection and disorders of the nervous system. Arch Neurol 1984; 41: 310–320.

    Article  PubMed  Google Scholar 

  168. Dorfman LJ: Cytomegalovirus encephalitis in adults. Neurology 1973; 23: 136–143.

    PubMed  CAS  Google Scholar 

  169. Chin W, Magoffin R, Frierson G, Lennette EH: Cytomegalovirus infection. A case of meningoencephalitis. JAMA 1973; 225: 740–741.

    Article  PubMed  CAS  Google Scholar 

  170. Duchowny M, Caplan L, Siber G: Cytomegalovirus infection of the adult nervous system. Ann Neurol 1979; 5: 458–461.

    Article  PubMed  CAS  Google Scholar 

  171. Linneman CC Jr, Dunn CR, First MR, et al: Late onset of fatal cytomegalovirus infection after renal transplantation. Primary or reactivation infection? Arch Intern Med 1978; 138: 1247–1250.

    Article  Google Scholar 

  172. Perham TGM, Caul EO, Clarke SKR, Gibson AGF: Cytomegalovirus meningoencephalitis. Br Med J 1971; 2: 50.

    Article  PubMed  CAS  Google Scholar 

  173. Philips CA, Fanning WL, Gump DW, Phillips CF: Cytomegalovirus encephalitis in immunologically normal adults. Successful treatments with vidarabine. JAMA 1977; 21: 2299–2300.

    Article  Google Scholar 

  174. Schneck SA: Neuropathological features of human organ transplantation. J Neuropathol Exp Neurol 1965; 24: 415–429.

    Article  Google Scholar 

  175. Schober R, Herman MM: Neuropathology of cardiac transplantation. Lancet 1973; 1: 962–967.

    Article  PubMed  CAS  Google Scholar 

  176. Yanagisaw N, Toyokura Y, Shiraki B: Double encephalitis with herpes simplex virus and cytomegalovirus in an adult. Acta Neuropathol (Berl) 1975; 33: 153–164.

    Article  Google Scholar 

  177. Reichert CM, O’Leary TJ, Levens DL, et al: Autopsy pathology in the acquired immune deficiency syndrome. Am J Pathol 1983; 112: 357–382.

    PubMed  CAS  Google Scholar 

  178. Detels R, Visscher BR, Fahey JL, et al: Predictors of clinical AIDS in young homosexual men in a high risk area. Int J Epidemiol 1987; 16: 271–276.

    Article  PubMed  CAS  Google Scholar 

  179. Koppel BS, Wormser GP, Tuchman AJ, et al: Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS). Acta Neurol Scand 1985; 71: 337–353.

    Article  PubMed  CAS  Google Scholar 

  180. Moskovitz LB, Gregorios JB, Hensley GT, Berger JR: Cytomegalovirus-induced demyelination associated with acquired immune deficiency syndrome. Arch Pathol Lab Med 1984; 108: 873–877.

    Google Scholar 

  181. Reichert CM, O’Leary TJ, Levens, DL: Autopsy pathology in the acquired immune deficiency syndrome. Am J Pathol 1983; 112: 357–382.

    PubMed  CAS  Google Scholar 

  182. Vital C, Vital A, Vignoly B, et al: Cytomegalovirus encephalitis in a patient with acquired immunodeficiency syndrome. Arch Pathol Lab Med 1985; 109: 105–106.

    PubMed  CAS  Google Scholar 

  183. Welsh K, Finkbeiner W, Alpers CE, et al: Autopsy findings in the acquired immune deficiency syndrome. JAMA 1984; 252: 1152–1159.

    Article  Google Scholar 

  184. Hawley DA, Schaefer JF, Schulz DM, Muller J: Cytomegalovirus encephalitis in acquired immunodeficiency syndrome. Am J Clin Pathol 1983; 80: 874–877.

    PubMed  CAS  Google Scholar 

  185. Wiley CA, Nelson JA: Role of human immunodeficiency virus and cytomegalovirus in AIDS encephalitis. Am J Pathol 1988; 33: 73–81.

    Google Scholar 

  186. Pepose JS, Hilborne LH, Cancilla PA, Foos RY: Concurrent herpes simplex and cytomegalovirus retinitis and encephalitis in the acquired immune deficiency syndrome (AIDS). Ophthalmology 1984; 91: 1669–1677.

    PubMed  CAS  Google Scholar 

  187. Wiley CA, Schrier RD, Denaro FJ, et al: Localization of cytomegalovirus proteins and genome during fulminant central nervous system infection in an AIDS patient. J Neuropathol Exp Neurol 1986; 45: 127–139.

    Article  PubMed  CAS  Google Scholar 

  188. Grafe MR, Wiley CA: Spinal cord and peripheral nerve pathology in AIDS: the roles of cytomegalovirus and human immunodeficiency virus. Ann Neurol 1989; 25: 561–566.

    Article  PubMed  CAS  Google Scholar 

  189. Dix RD, Bredesen DE: Opportunistic viral infections in acquired immunodeficiency syndrome, in ML Rosenblum, RM Levy, DE Bredesen (eds): AIDS and the Nervous System. New York, Raven Press, 1988, pp 221–261.

    Google Scholar 

  190. Dix RD, Bredesen DE, Erlich KS, Mills J: Recovery of herpesviruses from cerebrospinal fluid of immunodeficient homosexual men. Ann Neurol 1985; 18: 611–614.

    Article  PubMed  CAS  Google Scholar 

  191. Edwards RH, Messing R, McKendall RR: Cytomegalovirus meningoencephalitis in a homosexual 20. AIDS and Other Immunocompromised States 299 man with Kaposi’s sarcoma: isolation of CMV from CSF cells. Neurology 1985; 35: 560–562.

    PubMed  CAS  Google Scholar 

  192. Morgello S, Cho ES, Nielsen S, et al: Cytomegalovirus encephalitis in patients with acquired immunodeficiency syndrome: an autopsy study of 30 cases and a review of the literature. Hum Pathol 1987; 18: 289–297.

    Article  PubMed  CAS  Google Scholar 

  193. Vinters HV, Kwok MK, Ho HW, et al: Cytomegalovirus in the nervous system of patients with the acquired immune deficiency syndrome. Brain 1989; 112: 245–268.

    Article  PubMed  Google Scholar 

  194. Post MJ, Hensley GT, Moskowitz LB, et al: Cytomegalic inclusion virus encephalitis in patients with AIDS: CT, clinical, and pathologic correlation. AJR 1986; 146: 1229–1234.

    PubMed  CAS  Google Scholar 

  195. Skolnik PR, Kosloff BR, Hirsch MS: Bidirectional interactions between human immunodeficiency virus type 1 and cytomegalovirus. J Infect Dis 1988; 157: 508–514.

    Article  PubMed  CAS  Google Scholar 

  196. Mar EC, Cheng YC, Huang ES: Effect of 9-(1,3dihydroxy-2-propoxymethyl) guanine on human cytomegalovirus in vitro. Antimicrob Agents Che-mother 1983; 24: 518–521.

    CAS  Google Scholar 

  197. Pepose JS, Newman C, Bach MC, et al: Pathologic features of cytomegalovirus retinopathy after treatment with the antiviral agent ganciclovir. Ophthalmology 1987; 94: 41–424.

    Google Scholar 

  198. Felsenstein D, D’Amico DJ, Hirsch MS, et al: Treatment of cytomegalovirus retinitis with 9-(2hydroxymethyl) ethoxymethyl)guanine. Ann Intern Med 1985; 103: 377–380.

    PubMed  CAS  Google Scholar 

  199. Laskin OL, Cederberg DM, Mills J, et al: Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus. Am J Med 1987; 83: 201–207.

    Article  PubMed  CAS  Google Scholar 

  200. Walmsley SL, Chew E, Read SE, et al: Treatment of cytomegalovirus retinitis with trisodium phosphonoformate hexahydrate (Foscarnet). J Infect Dis 1988; 157: 569–572.

    Article  PubMed  CAS  Google Scholar 

  201. Le Hoang P, Girard B, Robinet M, et al: Foscarnet in the treatment of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology 1989; 96: 865–874.

    Google Scholar 

  202. Martin JH, Dohner DE, Wellinghoff WJ, Gelb LD: Restriction endonuclease analysis of varicella-zoster vaccine virus and wild-type DNAs. J Med Virol 1982; 9: 69–76.

    Article  PubMed  CAS  Google Scholar 

  203. Straus SE, Hay J, Smith H, Owens J: Genome differences among varicella-zoster virus isolates. J Gen Virol 1983; 64: 1031–1041.

    Article  PubMed  CAS  Google Scholar 

  204. Gelb LD: Varicella-zoster virus, in Fields BN, Knipe DM, Chanock RM, et al (eds): Virology. New York, Raven Press, 1985, pp 591–627.

    Google Scholar 

  205. Kestelyn P, Stevens AM, Bakkers E, et al: Sever hepes zoster ophthalmicus in young African adults: a marker for HTLV-III seropositivity. Br J Ophthalmol 1987; 71: 806–809.

    Article  PubMed  CAS  Google Scholar 

  206. McKendall RR, Klawans HL: Nervous system complications of varicella-zoster virus, in Vinken Pi, Bruyn GW (eds): Handbook of Clinical Neurology,Vol 34. New York, North-Holland, 1978, pp 161183.

    Google Scholar 

  207. Jemsek J, Greenberg SB, Taber L, et al: Herpes zoster-associated encephalitis: clinicopathologic report of 12 cases and review of the literature. Medicine 1983; 62: 81–97.

    Article  PubMed  CAS  Google Scholar 

  208. Ryder JW, Croen D, Kleinschmidt-DeMasters BK, et al: Progressive encephalitis 3 months after resolution of cutaneous zoster in a patient with AIDS. Ann Neurol 1986; 19: 182–188.

    Article  PubMed  CAS  Google Scholar 

  209. Gilden DH, Murray RS, Wellish BS, et al: Chronic progressive varicella-zoster virus encephalitis in an AIDS patient. Neurology 1988; 38: 1150–1153.

    PubMed  CAS  Google Scholar 

  210. Miller JR, Barrett RE, Britton CB, et al: Progressive multifocal leukoencephalopathy in a male homosexual with T-cell immune deficiency syndrome. N Engl J Med 1982; 307: 1436–1438.

    Article  PubMed  CAS  Google Scholar 

  211. Berger JR, Kaszovitz B, Post MJD, et al: Progressive multifocal leukoencephalopathy associated with human immunodeficiency virus infection: a review of the literature with a report of 16 cases. Ann Intern Med 1987; 107: 78–87.

    PubMed  CAS  Google Scholar 

  212. Houff SA, Major EO, Katz DA, et al: Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. N Engl J Med 1988; 318: 301–305.

    Article  PubMed  CAS  Google Scholar 

  213. Berger JR, Mucke L: Prolonged survival and partial recovery in AIDS-associated progressive multifocal leukoencephalopathy. Neurology 1988; 38: 1060–1064.

    PubMed  CAS  Google Scholar 

  214. Whimbey E, Gold JWM, Polsky B, et al: Bacteremia and fungemia in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1986; 10: 511–514.

    Google Scholar 

  215. Levy RM, Pons VG, Rosenblum ML: Central nervous system mass lesions in the acquired immunodeficiency syndrome (AIDS). J Nerosurg 1984; 61: 9–16.

    Article  CAS  Google Scholar 

  216. Kelly WM, Brant-Zawadzki M: Acquired immunodeficiency syndrome: neuroradiologic findings. Radiology 1983; 149: 485–491.

    PubMed  CAS  Google Scholar 

  217. Henin D, Duycaerts C, Chaunu MP, et al: Etude neuropathologique de 31 cas de syndrome d’immuno-depression acquise. Rev Neurol 1987; 143: 631–642.

    PubMed  CAS  Google Scholar 

  218. Pitchenik AE, Burr J, Fertel D, et al: Human T-cell lymphotropic virus III (HTLV III) seropositivity and related disease among 71 consecutive patients in whom tuberculosis was diagnosed. A prospective study. Am Rev Resp Dis 1987; 135: 875–879.

    PubMed  CAS  Google Scholar 

  219. Chaisson RE, Schecter GF, Theuer CP, et al: Tuberculosis in patients with the acquired immunodeficiency syndrome. Clinical features, response to therapy, and survival. Am Rev Resp Dis 1987; 136: 570–574.

    Article  PubMed  CAS  Google Scholar 

  220. Bishburg E, Sunderam G, Reichman LB, et al: Central nervous system tuberculosis with the acquired immunodeficiency syndrome and its related complex. Ann Intern Med 1986; 105: 210–213.

    PubMed  CAS  Google Scholar 

  221. Doll DC, Yarbro JW: Mycobacterial spinal cord abscess with an ascending polyneuropathy (letter). Ann Intern Med 1987; 106: 333–334.

    PubMed  CAS  Google Scholar 

  222. Centers for Disease Control: Diagnosis and management of mycobacterial infection and disease in persons with human immunodeficiency virus infection. Ann Intern Med 1987; 106: 204–206.

    Google Scholar 

  223. Pons VG, Jacobs RA, Hollander H: Nonviral infections of the central nervous system in patients with acquired immunodeficiency syndrome, in Rosenblum ML, Levy RM, Bredesen DE (eds): AIDS and the Central Nervous System. New York, Raven Press, 1988, pp 263–283.

    Google Scholar 

  224. Sharer LR, Kapila R: Neuropathologic observations in the acquired immunodeficiency syndrome. Acta Neuropathol 1985; 66: 188–198.

    Article  PubMed  CAS  Google Scholar 

  225. Adair JC, Beck AC, Apfelbaum RI, Baringer JR: Nocardial cerebral abscess in the acquired immunodeficiency syndrome. Arch Neurol 1987; 44: 548–50.

    Article  PubMed  CAS  Google Scholar 

  226. Holtz HA, Lavery DP, Kapila R: Actinomcetales infection in the acquired immunodeficiency syndrome. Acta Neuropathol 1985; 66: 203–205.

    Google Scholar 

  227. Viroslav J, Williams T: Nocardial infection of the pulmonary and central nervous system: successful treatment with medical therapy. South Med J 1971; 64: 1382–1385.

    Article  PubMed  CAS  Google Scholar 

  228. Byrne E, Brophy BP, Perrett LV: Nocardia cerebral abscess: new concepts in diagnosis, management, and prognosis. J Neurol Neurosurg Psychiatry 1979; 42: 1038–1045.

    Article  PubMed  CAS  Google Scholar 

  229. Berger JR, McCarthy M, Resnick L, et al: History of syphilis as a cofactor for the expression of HIV infection (abstract). Fifth International Conference on AIDS, Montreal, 1989, p 93.

    Google Scholar 

  230. Katz D, Berger JR: Neurosyphilis in AIDS. Arch Neurol 1989; 46: 895–901.

    Article  PubMed  CAS  Google Scholar 

  231. ’. Johns DR, Tierney M, Felsenstein D: Alteration in the natural history of neurosyphilis by concurrent infection with the human immunodeficiency virus. N Engl J Med 1987; 316: 1569–1572.

    Article  Google Scholar 

  232. Berry CD, Hooton TM, Collier AC, et al: Neurologic relapse after benzathine penicillin therapy for secondary syphilis in a patient with HIV infection. N Engl J Med 1987; 316: 1587–1589.

    Article  PubMed  CAS  Google Scholar 

  233. Chung WM, Pien FD, Grekin JL: Syphilis: a cause of fever of unknown origin. Cutis 1983; 31: 537–540.

    PubMed  CAS  Google Scholar 

  234. Zambrano W, Perez GM, Smith JL: Acute syphilitic blindness in AIDS. J Clin Neurol Opthalmol 1987; 7: 1–5.

    CAS  Google Scholar 

  235. Fernandez-Guerrero ML, Miranda C, Cenjor C, Sanabria F: The treatment of neurosyphilis in patients with HIV infection (letter). JAMA 1988; 259: 1495–1496.

    Article  PubMed  CAS  Google Scholar 

  236. Spence MR, Abrutyn E: Syphilis and infection with the human immunodeficiency virus. Ann Intern Med 1987; 107: 587.

    PubMed  CAS  Google Scholar 

  237. Haas JS, Bolan G, Larsen S, et al: “Seroreversion” of treponemal tests during HIV infection. Fifth International Conference on AIDS, Montreal, June 1989, p 360.

    Google Scholar 

  238. Hicks CB, Benson PM, Lupton GP, Tramont EC: Seronegative secondary syphilis in a patient infected with the human immunodeficiency virus (HIV) with Kaposi sarcoma. Ann Intern Med 1987; 107: 492–495.

    PubMed  CAS  Google Scholar 

  239. Editorial: Cryptococcus in AIDS. Lancet 1988; 25: 1434–1436.

    Google Scholar 

  240. Zuger A, Louie E, Holzman RS, et al: Cryptococcal disease in patients with the acquired immunodeficiency syndrome. Ann Intern Med 1986; 104: 234–240.

    PubMed  CAS  Google Scholar 

  241. Centers for Disease Control: Update: Acquired immunodeficiency syndrome-United States. MMWR 1986; 35: 542.

    Google Scholar 

  242. Pizzo PA, Eddy J, Faloon J: Acquired immune deficiency syndrome in children. Current problems and therapeutic considerations. Am J Med 1988; 85: 195–202.

    PubMed  CAS  Google Scholar 

  243. Kovacs JA, Kovacs AA, Polis M, et al: Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med 1985; 103: 533–538.

    PubMed  CAS  Google Scholar 

  244. Giberson TP, Kalyan-Raman K: Cryptococcal meningitis: initial presentation of acquired immunodeficiency syndrome. Ann Emerg Med 1987; 16: 802–804.

    Article  PubMed  CAS  Google Scholar 

  245. Gal AA, Evans S, Meyer PR: The clinical laboratory evaluation of cryptococcal infections in the acquired immunodeficiency syndrome. Diagn Microbiol Infect Dis 1987; 7: 249–254.

    Article  PubMed  CAS  Google Scholar 

  246. Kapend K, Komichelo K, Swinne D, et al: Meningitis due to Cryptococcus neoformans biovar gattii in a Zairian AIDS patient. Eur J Clin Microbiol Infect Dis 1987; 6: 320–321.

    Google Scholar 

  247. St-Germain G, Noel G, Chung KJ: Disseminated cryptococcosis due to Cryptococcus neoformans variety gattii in a Canadian patient with AIDS (letter). Eur J Clin Microbiol Infect Dis 1988; 7: 587–588.

    Article  PubMed  CAS  Google Scholar 

  248. Schimpff SC, Bennett JE: Abnormalities in cell-mediated immunity in patients with Cryptococcus neoformans infection. J Allerg Clin Immunol 1975; 55: 43–041.

    Article  Google Scholar 

  249. Dromer F, Aucouturier P, Clauvel JP, et al: Cryptococcus neoformans anitbody levels in patients with AIDS. Scand J Infect Dis 1988; 20: 283–285.

    Article  PubMed  CAS  Google Scholar 

  250. Sabetta JR, Andriole VT: Cryptococcal infection of 20. AIDS and Other Immunocompromised States 301 the central nervous system. Med Clin North Am 1985; 69: 333–344.

    PubMed  CAS  Google Scholar 

  251. Johannessen DJ, Wilson LG: Mania with cryptococcal meningitis in two AIDS patients. J Clin Psychiatr 1988; 49: 200–201.

    CAS  Google Scholar 

  252. Maayan S, Wormser GP, Hewlett D, et al: Acquired immunodeficiency syndrome (AIDS) in an economically disadvantaged population. Arch Intern Med 1985; 145: 1607–1612.

    Article  PubMed  CAS  Google Scholar 

  253. Diamond RD, Bennett JE: Prognostic factors in cryptococcal meningitis. A study of 111 cases. Ann Intern Med 1974; 80: 176–181.

    PubMed  CAS  Google Scholar 

  254. Kelly WM, Brant-Zawadzki M: Acquired immunodeficiency syndrome: neuroradiologic findings. Radiology 1983; 149: 485–491.

    PubMed  CAS  Google Scholar 

  255. Post MJD, Kursunoglu SJ, Hensley GT, et al: Cranial CT in acquired immunodeficiency syndrome: spectrum of diseases and optimal contrast enhancement technique. AJR 1985; 145: 929–940.

    PubMed  CAS  Google Scholar 

  256. Whelan MA, Kricheff II, Handler M, et al: Acquired immunodeficiency syndrome: cerebral computed tomographic manifestations. Radiology 1983; 149: 477–484.

    PubMed  CAS  Google Scholar 

  257. Larsen RA, Bozetta S, McCutchan JA, et al: California Collaborative Treatment Group: persistence of Cryptococcus neoformans infection of the prostate after successful treatment of meningitis. Ann Intern Med 1989; 111: 125–128

    PubMed  CAS  Google Scholar 

  258. Stern JJ, Hartman BJ, Sharkey P, et al: Oral fluconazole therapy for patients with acquired immunodeficiency syndrome and cryptococcosis: experience with 22 patients. Am J Med 1988; 85: 477–480.

    Article  PubMed  CAS  Google Scholar 

  259. Dismukes WE, Cloud G, Gallis HA, et al: Treatment of cryptococcal meningitis with combination amphotericin and flucytosine for four as compared to six weeks. N Engl J Med 1987; 317: 334–341.

    Article  PubMed  CAS  Google Scholar 

  260. Poon M, Cronin DC, Wormser GP, Bottone EJ: In vitro susceptibility of Cryptococcus neoformans isolates from patient with acquired immunodeficiency syndrome. Arch Pathol Lab Med 1988; 112: 16 1162.

    Google Scholar 

  261. Sugar AM, Saunders C: Oral fluconazole as suppressive therapy of disseminated cryptococcosis in patients with acquired immunodeficiency syndrome. Am J Med 1988; 85: 481–489.

    Article  PubMed  CAS  Google Scholar 

  262. Byrne WR, Wajszczuk CP: Cryptococcal meningitis in the acquired immunodeficiency syndrome (AIDS): successful treatment with fluconazole after failure of amphotericin B (letter). Ann Intern Med 1988; 108: 384–385.

    PubMed  CAS  Google Scholar 

  263. Diamond RD, Bennett JE: Prognostic factors in cryptococcal meningitis. Ann Intern Med 1974; 80: 176–181.

    PubMed  CAS  Google Scholar 

  264. Cuadrado LM, Guerrero A, Lopez Garcia Asenjo JA, et al: Cerebral mucormycosis in two cases of the acquired immunodeficiency syndrome. Arch Neurol 1988; 45: 109–111.

    Article  PubMed  CAS  Google Scholar 

  265. Micozzi MS, Wetli CV: Intravenous amphetamine abuse, primary cerebral mucormycosis, and acquired immunodeficiency. J Forensic Sci 1985; 30: 504–510.

    PubMed  CAS  Google Scholar 

  266. Petito CK, Cho ES, Lemann W, et al: Neuropathology of acquired immunodeficiency syndrome (AIDS): an autopsy review. J Neuropathol Exp Neurol 1986; 45: 635–646.

    Article  PubMed  CAS  Google Scholar 

  267. Wong B, Gold JWM, Brown AE, et al: Central nervous system toxoplasmosis in homosexual men and parenteral drug abusers. Ann Intern Med 1984; 100: 36–42.

    PubMed  CAS  Google Scholar 

  268. Wanke C, Tuazon CU, Kovacs A, et al: Toxoplasma encephalitis in patients with acquired immunodeficiency syndrome: diagnosis and response to therapy. Am J Trop Med Hyg 1987; 36: 509–516.

    PubMed  CAS  Google Scholar 

  269. Bia FJ, Barry M: Parasitic infections of the central nervous system. Neurol Clin 1986; 171–206.

    Google Scholar 

  270. Navia BA, Petito CK, Gold JW, et al: Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients. Ann Neurol 1986; 19: 224–238.

    Article  PubMed  CAS  Google Scholar 

  271. Nath A, Jankovic J, Pettigrew LC: Movement disorders and AIDS. Neurology 1987; 37: 37–41.

    PubMed  CAS  Google Scholar 

  272. Leport C, Vilde JL, Katlama C, et al: Toxoplasmose cerebrate de l’immunodeprime: diagnostic et traitement. Ann Med Interne 1987; 138: 30–33.

    CAS  Google Scholar 

  273. Holland GN, Enstrom RE Jr, Glasgow BJ, et al: Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome. Am J Ophthalmol 1988; 106: 653–667.

    PubMed  CAS  Google Scholar 

  274. Tschihart D, Klatt EC: Disseminated toxoplasmosis in the acquire immunodeficiency syndrome. Arch Pathol Lab Med 1988; 112: 1237–1241.

    Google Scholar 

  275. Touboul JL, Salmon D, Lancastre F, et al: Toxoplasma gondii pneumopathy in a patient with the acquired immunodeficiency syndrome: demonstration of the parasite by bronchioalveolar lavage. Rev Pneumol Clin 1986; 42: 150–152.

    PubMed  CAS  Google Scholar 

  276. Israelski DM, Skowron G, Leventhal JP, et al: Toxoplasma peritonitis in a patient with acquired immunodeficiency syndrome. Arch Intern Med 1988; 148: 1655–1657.

    Article  PubMed  CAS  Google Scholar 

  277. Nistal M, Santana A, Paniaqua L, et al: Testicular toxoplasmosis in two men with acquired immunodeficiency syndrome (AIDS). Arch Pathol Lab Med 1986; 110: 744–746.

    PubMed  CAS  Google Scholar 

  278. Hirschmann JV, Chu AC: Skin lesions with disseminated toxoplasmosis in patient with the acquired immunodeficiency syndrome (letter). Arch Dermatol 1988; 124: 1446–1447.

    Article  PubMed  CAS  Google Scholar 

  279. Post MJD, Chan JC, Hensley GT, et al: Toxoplasma encephalitis in Haitian adults with acquired immunodeficiency syndrome: a clinical-pathologic-CT correlation. AJNR 1983; 4: 155–162.

    Google Scholar 

  280. Nolla-Salas J, Ricart C, D’Olhaberriague L, et al: Hydrocephalus: an unusual CT presentation of cerebral toxoplasmosis in a patient with acquired immunodeficiency syndrome. Eur Neurol 1987; 27: 130–132.

    Article  PubMed  CAS  Google Scholar 

  281. Krol G, Becker R, Zimmerman R, et al: Contribution of MRI to the diagnosis of intracranial complications of acquired immune deficiency syndrome. Neuroradiology 1986: 99–104.

    Google Scholar 

  282. Levy RM, Rosenbloom S, Perrett LV: Neuroradiologic findings in AIDS: a review of 200 cases. AJR 1986; 147: 977–983.

    PubMed  CAS  Google Scholar 

  283. Jarvik JG, Hesselink JR, Kennedy C, et al: Acquired immunodeficiency syndrome. Magnetic resonance patterns of brain involvement with pathologic correlation. Arch Neurol 1988; 45: 731–736.

    Article  PubMed  CAS  Google Scholar 

  284. Farkash AE, Maccabee PJ, Sher JH, et al: CNS toxoplasmosis in acquired immunodeficiency syndrome: a clinical-pathological-radiological review of 12 cases. J Neurol Neurosurg Psychiatry 1986; 49: 744–748.

    Article  PubMed  CAS  Google Scholar 

  285. Luft BJ, Brooks RG, Conley FK, et al: Toxoplasmic encephalitis in patients with acquired immune deficiency syndrome. JAMA 1984; 252: 913–917.

    Article  PubMed  CAS  Google Scholar 

  286. Weiss LM, Udem SA, Tanowitz H, Wittner M: Western blot analysis of the antibody response of patients with AIDS and toxoplasma encephalitis: antigenic diversity among Toxoplasma strains. J Infect Dis 1988; 157: 7–13.

    Article  PubMed  CAS  Google Scholar 

  287. Potasman I, Resnick L, Luft BJ, Remington JS: Intrathecal production of antibodies against Toxoplasma gondii in patients with toxoplasmic encephalitis and the acquired immunodeficiency syndrome (AIDS). Ann Intern Med 1988; 108: 49–51.

    PubMed  CAS  Google Scholar 

  288. Hofflin JM, Remington JS: Tissue culture isolation of Toxoplasma from blood of a patient with AIDS. Arch Intern Med 1985; 145: 925–926.

    Article  PubMed  CAS  Google Scholar 

  289. DeMent SH, Cox M, Gupta PK: Diagnosis of central nervous system Toxoplasma gondii from the cerebrospinal fluid in a patient with acquired immunodeficiency syndrome. Diagn Cytopathol 1987; 3: 148–151.

    Article  PubMed  CAS  Google Scholar 

  290. Threlkeld MG, Graves AH, Cobbs CG: Cerebrospinal fluid staining for the diagnosis of toxoplasmosis in patients with the acquired immune deficiency syndrome (letter). Am J Med 1987; 83: 599–600.

    Article  PubMed  CAS  Google Scholar 

  291. Horowitz S, Bentson JR, Benson DF, et al: CNS toxoplasmosis in acquired immunodeficiency syndrome. Arch Neurol 1983; 40: 649–652.

    Article  PubMed  CAS  Google Scholar 

  292. Huang TE, Chou SM: Occlusive hypertrophic arteritis as the cause of discrete necrosis in CNS toxoplasmosis in the acquired immunodeficiency syndrome. Hum Pathol 1988; 19: 1210–1214.

    Article  PubMed  CAS  Google Scholar 

  293. Ruskin J, Remington JS: Toxoplasmosis in the compromised host. Ann Intern Med 1976; 84: 193–199.

    PubMed  CAS  Google Scholar 

  294. Haverkos HW: Assessment of therapy for toxoplas ma encephalitis. The TE study group. Am J Med 1987; 82: 907–914.

    Article  PubMed  CAS  Google Scholar 

  295. Sahai J, Heimberger T, Collins K, et al: Sulfadiazine-induced crystalluria in a patient with acquired immunodeficiency syndrome: a reminder. Am J Med 1988; 84: 791–792.

    Article  PubMed  CAS  Google Scholar 

  296. Leport C, Raffi F, Matheron B, et al: Treatment of central nervous system toxoplasmosis with pyrimethamine/sulfadiazine combination in 35 patients with the acquired immunodeficiency syndrome: efficacy of long term continuous therapy. Am J Med 1988; 84: 94–100.

    Article  PubMed  CAS  Google Scholar 

  297. Rolston KV, Hoy J: Role of clindamycin in the treatment of central nervous system toxoplasmosis. Am J Med 1987; 83: 551–554.

    Article  PubMed  CAS  Google Scholar 

  298. Danneman BR, Israelski DM, Remington JS: Treatment of toxoplasmic encephalitis with intravenous clindamycin. Arch Intern Med 1988; 148: 2477–2482.

    Article  Google Scholar 

  299. Wiley CA, Safrin RE, Davis CE, et al: Acanthamoeba meningoencephalitis in a patient with AIDS. J Infect Dis 1987; 155: 130–133.

    Article  PubMed  CAS  Google Scholar 

  300. Barin F, M’Boup S, Denis F, et al: Serological evidence for cirus related to simian T-lymphotropic retrovirus III in residents of West Africa. Lancet 1985; 2: 1387–1389.

    Article  PubMed  CAS  Google Scholar 

  301. Clavel F, Guetard D, Brun-Vezinet F, et al: Isolation of a new human retrovirus from West African patients with AIDS. Science 1986; 233: 343–346.

    Article  PubMed  CAS  Google Scholar 

  302. Clavel F, Mansinho K, Chamaret S, et al: Human immunodeficiency virus type 2 infection associated with AIDS in West Africa. N Engl J Med 1986; 316: 1180–1185.

    Article  Google Scholar 

  303. Editorial: HIV-2 in perspective. Lancet 1988; 1: 1027–1028.

    Google Scholar 

  304. Centers for Disease Control: AIDS due to HIV-2 infection-New Jersey. MMWR 1987; 37: 33–35.

    Google Scholar 

  305. Centers for Disease Control: Update: HIV-2 infection-United States. MMWR 1989; 38: 572–580.

    Google Scholar 

  306. Clavel F: Editorial review: HIV-2, the West African AIDS virus. AIDS 1987; 1: 35–40.

    Google Scholar 

  307. Denis F, Leonard G, Sangare A, et al: Comparison of 10 enzyme immunoassays for detection of antibody to human immunodeficiency virus type 2 in West African sera. J Clin Microbiol 1988; 26: 1000 1004.

    Google Scholar 

  308. Jackson JB, Balfour HH Jr: Practical diagnostic testing for human immunodeficiency virus. Clin Microbiol Rev 1988; 1: 124–138.

    PubMed  CAS  Google Scholar 

  309. Schochetman G, Ou C-Y, Jones WK: Polymerase chain reaction. J Infect Dis 1988; 158: 1154–1157.

    Article  PubMed  CAS  Google Scholar 

  310. Ancelle R, Bletry O, Baglin AG, et al: Long incubation period for HIV-2 infection. Lancet 1987; 1: 688–689.

    Article  PubMed  CAS  Google Scholar 

  311. Klemm E, Schneweis KE, Horn R, et al: HIV-II infection with initial neurological manifestation. J Neurol 1988; 235: 304–307.

    Article  PubMed  CAS  Google Scholar 

  312. Belec L, Martin PM, Georges-Courbot MC, et al: Dementia as the primary manifestation of HIV-2 infection in a Central African patient. Ann Inst Pasteur Virol 1988; 139: 291–294.

    Article  PubMed  CAS  Google Scholar 

  313. Brun-Vesinet F, Katlama C, Roulot D, et al: Lymphadenopathy-associated virus type 2 in AIDS and AIDS-related complex. Lancet 1987, 1: 128–132.

    Article  Google Scholar 

  314. Simpson JF: Listeria monocytogenes meningitis: an opportunistic infection. J Neurol Neurosurg Psychiatry 1971; 34: 657–663.

    Article  PubMed  CAS  Google Scholar 

  315. Gantz NM, Myerowitz RL, Medeiros AA, et al: Listerosis in immunosuppressed patients. A cluster of eight cases. Am J Med 1975; 58: 627–643.

    Article  Google Scholar 

  316. Chernik NL, Armstrong D, Posner JV: Central nervous system infections in patients with cancer: changing patterns. Cancer 1977; 40: 268–274.

    Article  PubMed  CAS  Google Scholar 

  317. Hooper DC, Pruitt AA, Rubin RH: Central nervous system infection in the chronically immunosuppressed. Medicine 1982; 61: 166–188.

    Article  PubMed  CAS  Google Scholar 

  318. Gray ML, Killinger AH: Listeria monocytogenes and listeric infections. Bacteriol Rev 1966; 30: 573.

    Google Scholar 

  319. Neiman RE, Lorber B: Listeriosis in adults: a changing pattern. Report of eight cases and review of the literature, 1968–1978. Rev Infect Dis 1980; 2: 207-227.

    Google Scholar 

  320. Weinstein AJ, Schiavone WA, Furlan AJ: Listeria rhomboencephalitis-report of a case. Arch Neurol 1982; 39: 514–516.

    Article  PubMed  CAS  Google Scholar 

  321. Lavetter A, Leedom JM, Mathies AW, et al: Meningitis due to Listeria monocytogenes. A review of 25 cases. N Engl J Med 1971; 285: 598–603.

    Article  PubMed  CAS  Google Scholar 

  322. Armstrong D: Listeria monocytogenes, in Mandell GL, Douglas RG Jr, Bennett JE (eds): Principles and Practice of Infectious Diseases, 2nd ed, New York, John Wiley and Sons, 1985, pp 1179–1182.

    Google Scholar 

  323. Watson GW, Fuller TJ, Elms J, Kluge RM: Listeria cerebritis: relapse of infection in renal transplant patients. Arch Intern Med 1978; 138: 83–87.

    Article  PubMed  CAS  Google Scholar 

  324. Fetter BF, Klintworth GK, Hendry WS: Mycosis of the Central Nervous System, Baltimore, Williams and Wilkins, 1967.

    Google Scholar 

  325. Causey WA, Lee R: Nocardia, in Vinken PJ, Bruyn GW (eds): Handbook of the Clinical Neurology, Vol 35, Amsterdam, North Holland Publishing Co, 1978, pp 517–530.

    Google Scholar 

  326. Law BJ, Marks MI: Pediatric nocardiosis. Pediatrics 1975; 55: 135.

    Google Scholar 

  327. Byrne E, Brophy BP, Pettett LV: Nocardia cerebral abscess: new concepts in diagnosis, management, and prognosis. J Neurol Neurosurg Psychiatry 1979; 42: 1038.

    Article  PubMed  CAS  Google Scholar 

  328. Scowden EB, Schaffner W, Stone WJ: Overwhelming strongyloidiasis: an unappreciated opportunistic infection. Medicine 1978; 57: 527–544.

    Article  PubMed  CAS  Google Scholar 

  329. Purtilo DT, Meyers WM, Connor DH: Fatal strongyloidiasis in immunosuppressed patients. Am J Med 1974; 56: 488.

    Article  PubMed  CAS  Google Scholar 

  330. Price RW, Navia BA: Infections in AIDS and in other immunosuppressed patients, in Kennedy PGE, Johnson RT (eds): Infections of the Nervous System. London, Butterworths, 1987, pp 247–273.

    Google Scholar 

  331. Lukes SA, Posner JB, Nielsen S, Armstrong D: Bacterial infection of the CNS in neutropenic patients. Neurology 1984; 34: 269–275.

    PubMed  CAS  Google Scholar 

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Berger, J.R., Levy, R.M., Dix, R. (1990). AIDS and Other Immunocompromised States. In: Schlossberg, D. (eds) Infections of the Nervous System. Clinical Topics in Infectious Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9698-7_20

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