Intellectual and Psychosocial Complications of Posterior Fossa Tumor Surgery and Supplemental (Radiation Therapy/Chemotherapy) Treatment

  • Elizabeth Hoppe-Hirsch
Part of the Principles of Pediatric Neurosurgery book series (PRINCPEDIATR)


Some remedies are worse than the disease. It might be alluring to apply this idea to the treatment of malignant posterior fossa tumors. This would not be quite relevant since, without treatment, death is the unavoidable result of the disease. However, the problem is not only to cure the tumor, but also to assure an acceptable quality of life for the child. From this point of view, in spite of the fact that the association of surgery and radiotherapy has remarkably increased the survival of children presenting with certain malignant neoplasms of the central nervous system, the enthusiasm of the pioneers should now be somewhat reduced. The improved survival rate overshadowed for a while the late therapy-related effects: intellectual impairment, endocrine dysfunction, and secondary neoplasms.


Acute Lymphocytic Leukemia Posterior Fossa Tumor Brain Stem Tumor Posterior Fossa Surgery Cerebellar Astrocytoma 
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© Springer-Verlag New York Inc. 1993

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  • Elizabeth Hoppe-Hirsch

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