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Photosensitizing Agents for Marrow Purging in Autologous Bone Marrow Transplantation

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Experimental Hematology Today—1989

Part of the book series: Experimental Hematology Today—1989 ((HEMATOLOGY,volume 1989))

Abstract

Most animal cells are insensitive to visible light because they lack chromophores that absorb at these wavelengths. However, cells can be made susceptible to visible light by staining them with a photosensitizing dye. Photosensitizers that bind preferentially to neoplastic cells offer interesting opportunities for new approaches to cancer therapy. The preferential retention of intravenously administered hematoporphyrin derivative (HPD) by tumor tissue is now exploited with encouraging results in the treatment of head and neck, lung, breast and bladder cancer, and several other solid tumors [1, 2].

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Authors
  1. F. Sieber
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Editors and Affiliations

  1. Department of Hematology, Saint-Antoine Hospital, 184, rue du Faubourg Saint-Antoine, 75571, Paris, France

    Norbert C. Gorin M.D.  & Luc Douay M.D.  & 

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Sieber, F. (1990). Photosensitizing Agents for Marrow Purging in Autologous Bone Marrow Transplantation. In: Gorin, N.C., Douay, L. (eds) Experimental Hematology Today—1989. Experimental Hematology Today—1989, vol 1989. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9003-9_2

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  • DOI: https://doi.org/10.1007/978-1-4613-9003-9_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9005-3

  • Online ISBN: 978-1-4613-9003-9

  • eBook Packages: Springer Book Archive

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