Abstract
The human cornea is about 0.52 mm thick at its center. It is composed of several layers, the innermost being the endothelium, which is a single layer of cells in contact with the aqueous humor. The endothelium consists of some 350,000 to 500,000 polygonal cells, approximately 5 mm thick, with straight-sided borders about 20 μm across. In a newborn baby the cells are almost all hexagonal and close-packed1; the cell density is approximately 4500 cells/sq mm. By the ninth decade of life the cell density can decrease to fewer than 1000 cells/sq mm, and the hexagons are less regular and mixed in with pentagons, heptagons, and other polygonal shapes.2–4
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Masters, B.R., Lee, YK., Rhodes, W.T. (1990). Fourier Transform Method for Statistical Evaluation of Corneal Endothelial Morphology. In: Masters, B.R. (eds) Noninvasive Diagnostic Techniques in Ophthalmology. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8896-8_8
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DOI: https://doi.org/10.1007/978-1-4613-8896-8_8
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