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Abstract

The size, structure, and wide host range of herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) make them suitable for use as vectors of genetic material both their own and that of foreign genomes. This chapter will describe in brief the unique structure of the HSV genome and the procedures used for selecting recombinant genomes, and illustrate the utility of this technology with specific examples of application.

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© 1989 Springer-Verlag New York Inc.

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Arsenakis, M., Roizman, B. (1989). Herpes Virus Vectors. In: Notkins, A.L., Oldstone, M.B.A. (eds) Concepts in Viral Pathogenesis III. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8890-6_8

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  • DOI: https://doi.org/10.1007/978-1-4613-8890-6_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8892-0

  • Online ISBN: 978-1-4613-8890-6

  • eBook Packages: Springer Book Archive

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