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Molecular Basis of Rhabdovirus Pathogenicity

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Abstract

The viruses of the family Rhabdoviridae are widely distributed in nature as disease-causing agents of plants, insects, fish, and mammals, including humans. A great deal is known about the structure, genetics, and molecular biology of rhabdoviruses, much of which are described in great detail in a book published in 1987 [1]. Most mammalian rhabdoviruses can be classified in two genera: Vesiculovirus, the prototype of which is vesicular stomatitis virus (VSV), and Lyssavirus, the major species being rabies virus. The rhabdovirus prototype VSV grows very rapidly to high titer and is cytopathogenic for almost all eucaryotic cells, thus providing an excellent model system for studying viral pathogenicity [2].

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References

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© 1989 Springer-Verlag New York Inc.

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Wagner, R.R. (1989). Molecular Basis of Rhabdovirus Pathogenicity. In: Notkins, A.L., Oldstone, M.B.A. (eds) Concepts in Viral Pathogenesis III. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8890-6_31

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  • DOI: https://doi.org/10.1007/978-1-4613-8890-6_31

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8892-0

  • Online ISBN: 978-1-4613-8890-6

  • eBook Packages: Springer Book Archive

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