Abstract
Alachlor [α-chloro-2′6′-diethyl-N-methoxymethylacetanilide or 2-chloro-N(2,6-diethylphenyl)-N-(methoxymethyl)acetamide], also known as Lasso®, is an herbicide whose major use (99%) is in preemergence application to field corn, soybeans, and peanuts. Its structure and properties are shown in Table 1.
Based on USEPA (1984a), except for Section I which is based on USEPA (1983a). Additions were included, where appropriate, from USEPA (1986a).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ahmed FE, Tegeris AS, Underwood PC, et al. (1981) Alachlor: six month study in the dog. Unpublished study submitted to USEPA by Monsanto Co. Report nos. CDL: 246292, 246293, and 247376.
Baker D (1982) Herbicide contamination in municipal water supplies in northwestern Ohio. Final draft report. Prepared for the USEPA Great Lakes National Program Office. (Cited in USEPA 1984b.)
Coleman DL and Gaffey WR (1980) A study of individuals exposed to alachlor: ocular examinations for uveitis. Unpublished study submitted to USEPA by Monsanto Co. Report no. CDL: 242943-A.
Daly IW, Hagan GK, Plutnick R, et al. (198la) An eighteen-month chronic feeding study of alachlor in mice. Unpublished study submitted to USEPA on July 1, 1981 by Monsanto Co. Report nos. CDL: 070168, 070169, and 247922.
Daly IW, McCandless JB, Jonassen H, et al. (1981b) A chronic feeding study of alachlor in rats. Unpublished study submitted to USEPA by Monsanto Co. Report nos. CDL: 070586, 070587, 070588, 070589, 070590, and 0247922.
DeFilippi RP, Kyukonis VJ, Robey RJ, Modell M (1980) Supercritical fluid regeneration of activated carbon for adsorption of pesticides. Publication No. EPA-600/280–054. USEPA, Research Triangle Park, NC.
IRDC (1980) A teratology study in rabbits. Study No. 401–060 dated Nov 24, 1980, submitted to USEPA, Jan 15, 1981. International Research and Development Corporation, Mattawan, MI. 49071. Report no. CDL: 244369.
IRDC (1984) A teratology study in rabbits. Study no. 401–208, initially submitted to USEPA, March 1, 1984 and amended later in 1984. International Research and Development Corporation, Mattawan, MI. 49071. Report no. CDL: 252570.
Monsanto Co (1978a) Acute studies: oral rat and acute dermal rabbit. Position document no. PD-77–433. Unpublished study submitted to USEPA by Bio-Dynamics, Inc. Report no. CDL: 241273.
Monsanto Co (1978b) Primary eye and primary dermal irritation—rabbit. Position document no. PD-77–433. Unpublished study submitted to USEPA by Bio-Dynamics, Inc. Report no. CDL: 241273.
Monsanto Co (1981a) Elimination of 14C-alachlor in monkeys. Study no. MA-81261. Submitted to USEPA by Monsanto Co. Report nos. CDL: 070592 and 247937.
Monsanto Co (1981b) Acute inhalation LD50—rat. Position document no. PD-1183. Unpublished study submitted to USEPA by Bio-Dynamics, Inc. Report no. CDL: 248053.
Monsanto Co (1982) Environmental fate of microencapsulated alachlor: Vols I & II. Unpublished study submitted to USEPA by Monsanto Agricultural Products Co. Report nos. CDL: 070841 and 248053.
Monsanto Co (1983) Rat metabolism study. Parts I and II. Unpublished study submitted to USEPA by Monsanto Co. Report nos. CDL: 251543 and 251544.
Monsanto Co (1984) Dermal sensitization—guinea pig. Unpublished study submitted to USEPA by Monsanto Co. Report no. CDL: 252772.
Monsanto Co (1985) The metabolism of alachlor in rhesus monkeys. Part II. Identification, characterization and quantification of alachlor and its metabolites after intravenous administration to monkeys. Special report MSL-5117. R.D. 641. October 30, 1985.
Naylor MW, Ribelin WE, Thake DE, Stout LD, Folks RM (1984) Chronic study of alachlor administered by gelatin capsule to dogs. Unpublished study no. 820165 submitted to USEPA by Environmental Health Laboratory, Monsanto Co, St. Louis, MO. Report no. CDL: 25593.
Rodwell DE and Tracher EP (1980) Teratology study in rats. Unpublished study prepared by International Research and Development Corp, submitted to USEPA by Monsanto Co. Report no. CDL: 243506.
Schroeder RD, Hogan GK, Smock ME, et al. (1981) A three-generation reproduction study in rats with alachlor. Project no. 77–2066. Unpublished study prepared by Bio-Dynamics Inc, submitted to USEPA by Monsanto Co. Report no. CDL: 070177-A.
Shirasu et al. (1980) Microbial mutagenicity study. Prepared by the Institute of Environmental Toxicology, Kodira, Japan, submitted to USEPA by Monsanto Co.
Stout LD et al. (1983a) A chronic study of alachlor administered in feed to Long-Evans rats. Vol I and II. Project no. ML-80–186. Unpublished study prepared by Monsanto Environmental Health Laboratory, submitted to USEPA by Monsanto Co. Report no. CDL: 252496–7.
Stout LD et al. (1983b) A chronic study of alachlor administered in feed to Long-Evans rats. Project no. ML-80–224. Unpublished study prepared by Monsanto Environmental Health Laboratory, submitted to USEPA by Monsanto Co. Report no. CDL: 252498.
USEPA (1983a) Occurrence of pesticides in drinking water, food, and air. USEPA Office of Drinking Water, Washington, DC.
USEPA (1983b) Determination of alachlor, butachlor, and propachlor in wastewater. Method 102. USEPA Effluent Guidelines Division, Washington, DC.
USEPA (1984a) Alachlor. Special review position document 1. Published Dec 31, 1984. USEPA Office of Pesticide Programs, Washington, DC.
USEPA (1984b) Review of treatability data for removal of twenty-five synthetic organic chemicals from drinking water. USEPA Office of Drinking Water, Washington, DC.
USEPA (1986a) Alachlor. Special review position documents 2 and 3. USEPA Office of Pesticide Programs, Washington, DC.
USEPA (1986b) Guidance for carcinogen risk assessment. Fed Regis 51(185)3399234003. September 24.
USEPA (1987a) Comments on various responses to the Agency’s Federal Register notice dated October 8, 1986 and the technical support document of alachlor. USEPA Office of Pesticide Programs, Washington, DC.
USEPA (1987b) Cancer Risk Assessment Verification Enterprise ( CRAVE ). Alachlor oncogenic risk verification.
USEPA (1987c) Alachlor. Special review position document 4. USEPA Office of Pesticide Programs, Washington, DC.
Windholz M, Budavari S, Blumetti RF, Otterbein ES (eds) (1983) The Merck indexan encyclopedia of chemicals and drugs. 10th Ed. Merck & Co Inc, Rahway, NJ, p 31.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag New York Inc.
About this chapter
Cite this chapter
Ware, G.W. (1988). Alachlor. In: Ware, G.W. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 104. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8785-5_2
Download citation
DOI: https://doi.org/10.1007/978-1-4613-8785-5_2
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4613-8787-9
Online ISBN: 978-1-4613-8785-5
eBook Packages: Springer Book Archive