Fate of Coronary Aneurysm in Kawasaki Disease: Analysis of Prognostic Factors

  • E. Ichinose
  • O. Inoue
  • Y. Hiyoshi
  • H. Kato

Abstract

We have previously reported that coronary aneurysms of Kawasaki disease in the acute stage have regressed to normal in half of the patients or have developed to ischemic heart disease in some patients by serial coronary angiographic studies [1–3]. Coronary angiography was performed in 508 patients within 3 months from the onset of illness, and coronary aneurysms were demonstrated in 136. Follow-up angiography was performed 1–2 years after the first study in 127 of 136 patients. It revealed the complete regression of coronary aneurysm in 72 of 127 patients (regress group); but in 55 patients, the coronary lesions have remained or developed to stenotic lesions (abnormal group). To elucidate the risk factors that could affect the prognosis of coronary aneurysms, we investigated the various factors, including sex, age at onset, maximal white blood cell counts, maximal platelet counts, maximal erythrocyte sedimentation rate, duration of fever, maximal diameter and shape of coronary aneurysm, and the methods of treatment (aspirin group/steroid group).

Keywords

Aspirin Sedimentation Cardiol Doyle Kato 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Kato H, Koike S, Yamamoto M, Ito Y, Yano E: Coronary aneurysms in infants and young children with mucocutaneous lymph node syndrome. J Pediatr86: 892, 1975.PubMedCrossRefGoogle Scholar
  2. 2.
    Kato H, Ichinose E, Yoshioka F, Takechi T, Matsynaga S, Suzuki K, Rikitake N: Fate of coronary aneurysms in Kawasaki disease: Serial coronary angiography and long-term follow-up study. Am J Cardiol49: 1758, 1982.PubMedCrossRefGoogle Scholar
  3. 3.
    Kato H, Ichinose E: Cardiovascular involvement in Kawasaki disease. Acta Paediatr Jpn26: 132, 1984.CrossRefGoogle Scholar
  4. 4.
    Kato H, Koike S, Yokoyama T: Kawasaki disease: Effect of treatment on coronary artery involvement. Pediatrics63: 175, 1979.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • E. Ichinose
  • O. Inoue
  • Y. Hiyoshi
  • H. Kato

There are no affiliations available

Personalised recommendations