Fate of Coronary Aneurysm in Kawasaki Disease: Analysis of Prognostic Factors
We have previously reported that coronary aneurysms of Kawasaki disease in the acute stage have regressed to normal in half of the patients or have developed to ischemic heart disease in some patients by serial coronary angiographic studies [1–3]. Coronary angiography was performed in 508 patients within 3 months from the onset of illness, and coronary aneurysms were demonstrated in 136. Follow-up angiography was performed 1–2 years after the first study in 127 of 136 patients. It revealed the complete regression of coronary aneurysm in 72 of 127 patients (regress group); but in 55 patients, the coronary lesions have remained or developed to stenotic lesions (abnormal group). To elucidate the risk factors that could affect the prognosis of coronary aneurysms, we investigated the various factors, including sex, age at onset, maximal white blood cell counts, maximal platelet counts, maximal erythrocyte sedimentation rate, duration of fever, maximal diameter and shape of coronary aneurysm, and the methods of treatment (aspirin group/steroid group).
KeywordsCoronary Angiography Kawasaki Disease Maximal Diameter Coronary Lesion Stenotic Lesion
Unable to display preview. Download preview PDF.