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Comparison between M-Mode and Digitized Echocardiography in the Detection of Anthracycline Cardiotoxicity

  • George G. S. Sandor
  • Paul C. J. Rogers
  • Ka-Wah Chan
  • Zubeda Sadaruddin
  • Marion Tipple
  • Michael W. H. Patterson
  • Shirley Hazell
  • Mavis Teasdale
  • Marty Puterman
Conference paper

Abstract

Since the description of the cardiotoxic effects of adriamycin and daunorubi­cin, different methods have been used to attempt noninvasive detection of this cardiotoxicity. These include following serial chest X-rays films, cardiac enzymes, electrocardiograms, systolic time intervals, m-mode echocardiogra­phy, two-dimensional echocardiography, and radionuclide cineangiography [1–3]. They are neither sensitive nor specific and, more importantly, do not detect early changes that might influence chemotherapeutic decisions. This study was performed to investigate the usefulness of digitized echocardiogra­phy to detect changes in cardiac function due to anthracyclines and to compare this technique with standard m-mode echocardiography [4].

Keywords

Left Ventricular Function Shorten Fraction Wall Velocity Cardiotoxic Effect Systolic Time Interval 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Von Hoff DD: The cardiotoxicity of commonly used antineoplastic agents. Adria Laboratories, 1980.Google Scholar
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    Von Hoff DD: Risk factors for development of daunorubicin cardiotoxity. Cancer Treat Rep 65 (Suppl 4): 19–23, 1981.Google Scholar
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    Upton MT, Gibson DG: The study of left ventricular function from digitized echocardiograms. Prog Cardiovasc Dis 20: 359–384, 1978.PubMedCrossRefGoogle Scholar
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    Florenzano F, Diaz G, Regonesi C, Escobar E: Left ventricular function in chronic anemia: Evidence of noncatecholamine positive inotropic factor in the serum. Am J Cardiol 54: 638–645, 1984.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • George G. S. Sandor
  • Paul C. J. Rogers
  • Ka-Wah Chan
  • Zubeda Sadaruddin
  • Marion Tipple
  • Michael W. H. Patterson
  • Shirley Hazell
  • Mavis Teasdale
  • Marty Puterman

There are no affiliations available

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