Comparison between M-Mode and Digitized Echocardiography in the Detection of Anthracycline Cardiotoxicity
Since the description of the cardiotoxic effects of adriamycin and daunorubicin, different methods have been used to attempt noninvasive detection of this cardiotoxicity. These include following serial chest X-rays films, cardiac enzymes, electrocardiograms, systolic time intervals, m-mode echocardiography, two-dimensional echocardiography, and radionuclide cineangiography [1–3]. They are neither sensitive nor specific and, more importantly, do not detect early changes that might influence chemotherapeutic decisions. This study was performed to investigate the usefulness of digitized echocardiography to detect changes in cardiac function due to anthracyclines and to compare this technique with standard m-mode echocardiography .
KeywordsLeft Ventricular Function Shorten Fraction Wall Velocity Cardiotoxic Effect Systolic Time Interval
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