An Endemic Cardiomyopathy in China: Ke Shan Disease
Ke Shan Disease (KSD) is an endemic myocardial disease that was first discovered in 1935 in Ke Shan county, Heilongjian province of northeast China. In the acute form, it manifests itself by sudden onset of precordial oppression, abdominal pain, and nausea and vomiting with fatal termination in severe cases. It was first suspected to be an acute infectious disease somewhat like plague, but it was soon proved to be a myocardial disease with necrotic lesions. In the past several decades, large numbers of children died of this disastrous disease.
KeywordsSelenium Cardiomyopathy Doyle Selenite Plague
Unable to display preview. Download preview PDF.
- 1.Gu BQ: Pathology of Ke Shan disease. A comprehensive review. Chin Med J 96 (4): 25l - 261, 1983.Google Scholar
- 2.He GQ: On the etiology of Ke Shan disease, 2 hypotheses. Chin Med J 92 (6): 416–442, 1979.Google Scholar
- 3.Ke Shan Disease Research Group of the Chinese Academy of Medical Science: Epidemiological studies on the etiologic relationship of selenium and Ke Shan disease. Chin Med J 92 (7): 477–482, 1979.Google Scholar