An Endemic Cardiomyopathy in China: Ke Shan Disease

  • Yang Shih-Yuen
Conference paper


Ke Shan Disease (KSD) is an endemic myocardial disease that was first discovered in 1935 in Ke Shan county, Heilongjian province of northeast China. In the acute form, it manifests itself by sudden onset of precordial oppression, abdominal pain, and nausea and vomiting with fatal termination in severe cases. It was first suspected to be an acute infectious disease somewhat like plague, but it was soon proved to be a myocardial disease with necrotic lesions. In the past several decades, large numbers of children died of this disastrous disease.


Selenium Deficiency Acute Form Acute Infectious Disease White Muscle Disease Subacute Form 
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© Springer Science+Business Media New York 1986

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  • Yang Shih-Yuen

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