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Ontogeny of Human T Cell Antigens

  • David F. Lobach
  • Lucinda L. Hensley
  • Winifred Ho
  • Barton F. Haynes

Abstract

During early fetal ontogeny, the thymic rudiment is formed by a combination of mesodermal, endodermal, and ectodermal elements (1–4). Between 9 and 10 weeks of fetal gestation, the human epithelial thymus is colonized by blood-borne T cell precursors (3–6). Cortical-medullary partitioning of the thymus occurs at 14–15 weeks of gestation and Hassall’s bodies, keratinized epithelial swirls in the medulla, first appear at 15–16 weeks of gestation (3–6). Thus by 16 weeks of gestation, thymic architecture resembles the morphology of postnatal thymus (3–6).

Keywords

Thymic Epithelial Cell Human Thymus Thymic Epithelium Fetal Gestation Monoclonal Reagent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1986

Authors and Affiliations

  • David F. Lobach
  • Lucinda L. Hensley
  • Winifred Ho
  • Barton F. Haynes

There are no affiliations available

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