Trichuriasis

  • Kenneth S. Warren
  • Adel A. F. Mahmoud

Abstract

Trichuriasis, or whipworm, is among the most prevalent of all the helminthic parasites of mankind; a conservative estimate is that more than half a billion individuals are infected.1 A recent survey of the literature suggested that there are 2.5 million individuals with trichuriasis in the continental United States, mainly in the rural southeast. A large-scale study in Puerto Rico revealed a 75% infection rate in 6-year-old children. Trichuris trichiura has an exceedingly simple life cycle, in which ingested eggs hatch in the small bowel and the larvae pass directly down into their final habitat in the colon. The head of the worm is embedded in the mucosa, from which it appears to take up minute amounts of blood. Most individuals with trichuriasis have relatively light infections of no clinical significance. Heavy infections, which occur mainly in young children, may result in disease manifestations. Whereas treatment in the past has been inadequate, an effective nontoxic drug has recently been developed.

Keywords

Anemia Diarrhea Malaysia Trop Eosinophilia 

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References

  1. 1.
    Beiding DL: Textbook of parasitology, 3rd edit, pp 397–402. Appleton-Century-Crofts, New York, 1965Google Scholar
  2. 2.
    Hartz PH: Histopathology of the colon in massive trichocephaliasis in children. Doc Med Geog Trop 5:303–313, 1953Google Scholar
  3. 3.
    Layrisse M, Aparcedo L, Martinez-Torres C, Roche M: Blood loss due to infection with Trichuris trichiura. Am J Trop Med Hyg 16:613–619, 1967PubMedGoogle Scholar
  4. 4.
    Otto GF: Blood studies on Trichuris-inksted and worm-free children in Louisiana. Am J Trop Med 15:693–704, 1935Google Scholar
  5. 5.
    Jung RC, Beaver PC: Clinical observations on Trichocephalus trichiurus (whipworm) infestation in children. Pediatrics 8:548–557, 1951PubMedGoogle Scholar
  6. 6.
    Gillman RH, Chavez YH, Davis C, Greenberg B, Virik HK, Dixon HB: The adverse consequences of heavy Trichuris infection. Trans R Soc Trop Med Hyg 77:423, 438, 1983CrossRefGoogle Scholar
  7. 7.
    Melvin DM, Brooke MM: Laboratory procedures for the diagnosis of intestinal parasites. U.S. Department of Health, Education, and Welfare (publication no. (CDC) 75–8282), pp 37, 38, 165. Atlanta, 1974Google Scholar
  8. 8.
    Med Lett Drugs Ther: Drugs for parasitic infections. 26:27–34, 1984Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1985

Authors and Affiliations

  • Kenneth S. Warren
    • 1
  • Adel A. F. Mahmoud
    • 2
  1. 1.Rockefeller FoundationNew YorkUSA
  2. 2.University Hospital of ClevelandClevelandUSA

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