Congenital Optic Disc Anomalies

  • Michael C. Brodsky
  • Robert S. Baker
  • Latif M. Hamed


Ophthalmologists and neurologists are frequently called upon to evaluate infants and children with decreased vision resulting from congenital anomalies of the optic disc. A comprehensive evaluation necessitates an understanding of the ophthalmoscopic features, associated neuro-ophthalmologic findings, pathogenesis, and appropriate ancillary studies for each anomaly. Over the past decade, new ocular and systemic associations have emerged, and theories of pathogenesis for many optic disc anomalies have been revised. Our increasing ability to subclassify different forms of excavated optic disc anomalies that were previously lumped together as colobomatous defects has further refined our ability to predict the likelihood of associated central nervous system (CNS) anomalies based solely on the appearance of the optic disc. Added to this has been the widespread clinical application of magnetic resonance (MR) imaging, which has refined our ability to identify subtle associated CNS anomalies and to predict the likelihood of associated neurodevelopmental and endocrinological problems. Based largely upon information that has emerged over the past decade, this chapter will examine the optic disc anomalies, summarize our current understanding of their pathogenesis and treatment, and detail associated neuroimaging findings that predicate the general medical management of affected children.


Optic Nerve Optic Disc Lamina Cribrosa Morning Glory Myelinated Nerve Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag New York, Inc. 1996

Authors and Affiliations

  • Michael C. Brodsky
    • 1
    • 2
  • Robert S. Baker
    • 3
  • Latif M. Hamed
    • 4
  1. 1.Jones Eye InstituteUniversity of Arkansas for Medical SciencesLittle RockUSA
  2. 2.Arkansas Children’sHospital Little RockUSA
  3. 3.University of Kentucky Medical CenterLexingtonUSA
  4. 4.Section of Pediatric OphtalmologyUniversity of Florida College of MedicineGainesvilleUSA

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