Basic Principles: “What You See Is What You Get”
Histology is largely a visual discipline. Observation is vitally important. For most students, as for Sherlock Holmes, the attainment of this facility of observing and reasoning on the basis ofobservation requires training and practice. In microscopy, as in detective work, one must not simply look; one must look with a system and an objective. The essence of scientific study is to observe and record differences and similarities among a group ofspecimens or circumstances using reliable criteria to determine these characteristics. By distinguishing and identifying form, dimension, and substance one can develop a useful morphologic construct ofcell, tissue, organ, or system. Also, by keeping in mind the physiologic capabilities of individual elements of entire organs and systems one can understand more easily the function of the whole.
KeywordsCholesterol Formalin Epoxy Aldehyde Dehydration
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