Abstract
In Chapter 19, a review of the salient features of the model of anti-tubular basement membrane (TBM) nephritis in guinea pigs was given. This discussion will focus upon certain additional aspects of this model and also comment briefly on experimental anti-TBM disease in rats. Finally, current knowledge of the role of anti-TBM antibodies in human renal disease will be reviewed.
Supported in part by NIH Grants 1 R01 AM 18729 and CA 19393.
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References
Andres, G. A., and McCluskey, R. T., 1975, Tubular and interstitial renal disease due to immunologic mechanisms, Kidney Int. 7:211.
Andres, G., Brentjens, J., Kohli, R., Anthone, R., Anthone, S., Baliah, T., Montes, M., Mookerjee, B. K., Prezyna, A., Sepulveda, M., Venuto, R., and Elwood, C., 1978, Histology of human tubulo-interstitial nephritis associated with antibodies to renal basement membranes, Kidney Int. 13:480.
Baldwin, D. S., Levine, B. B., McCluskey, R. T., and Gallo, G. R., 1968, Renal failure and interstitial nephritis due to penicillin and methicillin, N. Engl. J. Med. 279:1245.
Benacerraf, B., and McDevitt, H. O., 1972, Histocompatibility linked immune response genes, Science 175:273.
Bergstein, J.M., and Litman, N., 1975, Interstitial nephrids with antitubular basement membrane antibody, N. Engl. J. Med. 292:875.
Bloch, K. H., Kourilsky, F. M., Ovary, Z., and Benacerraf, B., 1963, Properties of guinea pigs 7S antibodies. III. Identification of antibodies involved in complement fixation and hemolysis, J. Exp. Med. 117:965.
Border, W. A., Lehman, D. H., Egan, J. D., Sass, H. J., Glode, J. E., and Wilson, C. B., 1974, Antitubular basement membrane antibodies in methicillin-associated interstitial nephritis, N. Engl. J. Med. 291:381.
Hall, C. L., Colvin, R. B., Carey, K., and McCluskey, R. T., 1977, Passive transfer of autoimmune disease with isologous IgG1 and IgG2 antibodies to the tubular basement membrane in strain XIII guinea pigs, J. Exp. Med. 146:1246.
Hyman, L. R., Colvin, R. B., and Steinberg, A. D., 1976a, Immunopathogenesis of autoimmune tubulointerstitial nephritis. I. Demonstration of differential susceptibility in strain II and strain XIII guinea pigs, J. Immunol. 116:327.
Hyman, L. R., Steinberg, A. D., Colvin, R. B., and Bernard, E. F., 1976b, Immunopathogenesis of autoimmune tubulointerstitial nephritis. II. Role of an immune response gene linked to the major histocompatibility locus, J. Immunol. 117:1894.
Hyman, L. R., Ballow, M., and Knieser, M. R., 1978, Diphenylhydantoin interstitial nephritis: Roles of cellular and humoral immunologic injury, J. Pediatr. 92:915.
Klassen, J., Kano, K., Milgrom, F., Menno, A. B., Anthone, S., Anthone, R., Sepulveda, M., Elwood, C. M., and Andres, G. A., 1973, Tubular lesions produced by autoantibodies to tubular basement membrane in human renal allografts, Int. Arch. Allergy Appl. Immunol. 45:675.
Lange, K., Wachstein, M., and McPherson, E. St., 1961, Immunological mechanism of transmission of experimental glomerulonephritis in parabiotic rats, Proc. Soc. Exp. Biol. Med. 106:13.
Lehman, D. H., and Wilson, C. B., 1976, Role of sensitized cells in antitubular basement membrane interstitial nephritis, Int. Arch. Allergy Appl. Immunol. 51:168.
Lehman, D. H., Wilson, C. B., and Dixon, F. J., 1974, Interstitial nephritis in rats immunized with heterologous tubular basement membrane, Kidney Int. 5:187.
Lockwood, C. M., Rees, A. J., Pearson, T. A., Evans, D. J., Peters, D. R., and Wilson, C. B., 1976, Immunosuppression and plasma-exchange in the treatment of Goodpasture’s syndrome, Lancet 1:711.
McCluskey, R. T., and Colvin, R. B., 1978, Immunological aspects of renal tubular and interstitial diseases, Annu. Rev. Med. 29:191.
Milgrom, F., and Dubiski, S., 1957, Mecanisme de l’autoimmunisation au cours des anemies hemolytique, Vox Sang. 27:11.
Mohn, J.R., Lambert, R. M., Bowman, H. S. and Brason, F. W., 1965, Experimental production in man of autoantibodies with Rh specificity, Ann. N.Y. Acad. Sci. 124:477.
Neilson, E. G., and Phillips, S. M., 1978, Cell-mediated lymphocytotoxicity in interstitial nephritis: In vitro and in vivo observations, Kidney Int. (abstract).
Oldstone, M. B. A., and Dixon, F. J., 1970, Pathogenesis of chronic disease associated with persistent lymphocytic choriomeningitis viral infection. II. Relationship of the anti-lymphocytic choriomeningitis immune response to tissue injury in chronic lymphocytic choriomeningitis disease, J. Exp. Med. 131:1.
Ooi, B. S., Ooi, Y. M., Mohini, R., and Pollak, V. E., 1978, Humoral mechanisms in drug induced acute interstitial nephritis, Clin. Immunol. Immunopathol. 10:330.
Porter, D. D., Larsen, A. E., and Porter, H. G., 1972, The pathogenesis of Aleutian disease of mink. II. Enhancement of tissue lesions following the administration of a killed virus vaccine or passive antibody, J. Immunol. 109:1.
Robertson, J. L., Hill, G. S., and Rowlands, D. T., 1977, Tubulointerstitial nephritis and glomerulonephritis in Brown Norway rats immunized with heterologous glomerular basement membrane, Am. J. Pathol. 88:53.
Rocklin, R. E., Lewis, E. J., and David, J. R., 1970, In vivo evidence for cellular hypersensitivity to glomerular basement membrane antigens in human glomerulonephritis, N. Engl. J. Med. 283:497.
Rudofsky, U. H., and Pollara, B., 1975, Studies on the pathogenesis of experimental autoimmune renal tubulointerstitial disease in guinea pigs. I. Inhibition of tissue injury in leukocytedepleted passive transfer recipients, Clin. Immunol. Immunopathol. 4:425.
Rudofsky, U. H., and Pollara, B., 1976, Studies on the pathogenesis of experimental autoimmune renal tubulointerstitial disease in guinea pigs. II. Passive transfer of renal lesions to leukocytedepleted recipients by anti-tubular basement membrane autoantibodies and non-immune bone marrow cells, Clin. Immunol. Immunopathol. 6:107.
Steblay, R. W., and Rudofsky, U. H., 1973, Transfer of experimental autoimmune renal cortical tubular and interstitial disease in guinea pigs by serum, Science 180:966.
Sugisaki, T., Klassen, J., Milgrom, F., Andres, G. A., and McCluskey, R. T., 1973, Immunopathologic study of an autoimmune tubular and interstitial renal disease in Brown Norway rats, Lab. Invest. 28:658.
Tomazic, V., and Rose, N. R., 1975, Autoimmune murine thyroiditis. VII. Induction of the thyroid lesions by passive transfer of serum, Clin. Immunol. Immunopathol. 4:511.
Unanue, E. R., and Dixon, F. J., 1965, Experimental glomerulonephritis: VI. The autologous phase of nephrotoxic serum nephritis, J. Exp. Med. 121
Van Zwieten, M. J., Bhan, A. K., McCluskey, R. T., and Collins, A. B., 1976, Studies on the pathogenesis of experimental anti-tubular basement membrane nephritis in the guinea pig, Am. J. Pathol. 83:531.
Vuagnat, P., 1974, Further studies on the biological properties of guinea pigs IgGi antibodies: Antilymphocytic antibodies, Immunology 27:351.
Wilson, C. B., and Dixon, F. J., 1973, Anti-glomerular basement membrane antibody-induced glomerulonephritis, Kidney Int. 3:74.
Wilson, C. B., Lehman, D. H., McCoy, R. C, Gunnels, J. C, Jr., and Stickel D. L., 1974, Antitubular basement membrane antibodies after renal transplantation, Transplantation 18:447.
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McCluskey, R.T., Bhan, A.K., Colvin, R.B. (1983). Experimental and Human Anti-Tubular Basement Membrane Nephritis. In: Cummings, N.B., Michael, A.F., Wilson, C.B. (eds) Immune Mechanisms in Renal Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4625-8_20
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DOI: https://doi.org/10.1007/978-1-4613-4625-8_20
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