Abstract
Although it has been established that carbohydrates are not the only energy source in skeletal muscle (Andres et al., 1956; Havel, et al., 1963; Bass & Hudlicka, 1964; Paul, 1970) it appears that a large part of energy supply for the performance of work is derived from the breakdown of glycogen (see e.g. Ahlborg et al., 1967; Corsi et al., 1969). In a dog gastrocnemius muscle glycogen is used mainly during the first 10–15 mm of rhythmic contractions (Hirche et al., 1970) at which time the work performed by this muscle is diminishing. An early onset of fatigue has been described in fast muscles (see e.g. del Pozo, 1942; Eberstein & Sandow, 1963) which have a high content of glycogen, while slow muscles where the content of glycogen is lower can work for a long time without signs of fatigue (Kugelberg & Edström, 1968; Edstr8m & Kugelberg, 1968). In order to elucidate these discrepancies consumpf ion of some substrates has been followed in isolated cat soleus (slow) and gastrocnemius (mainly fast) muscles in situ measuring the blood flow and A-V differences while the muscles have been performing isotonic contractions.
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Hudlicka, O. (1971). Uptake of Substrates in Isolated Contracting Slow and Fast Muscles in Situ in Relation to Fatigue. In: Pernow, B., Saltin, B. (eds) Muscle Metabolism During Exercise. Advances in Experimental Medicine and Biology, vol 11. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4609-8_20
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DOI: https://doi.org/10.1007/978-1-4613-4609-8_20
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