Metabolism of Free Fatty Acids and Ketone Bodies in Skeletal Muscle
Evaluation of the free fatty acid (FFA) metabolism in skeletal muscle at rest and during exercise has been rendered difficult by the finding of simultaneous release and uptake of FFA from muscle tissue (6, 14). Analysis of local FFA uptake and oxidation in muscle has therefore been based on the use of isotopic techniques (7, 11). The human forearm is a useful model for such studies both at rest and during exercise since it posesses a dominant single artery blood supply into which a tracer substance may be infused and venous blood can be obtained almost exclusively from muscle tissue via the deep forearm veins (12).
KeywordsFree Fatty Acid Ketone Body Plasma Free Fatty Acid Arterial Concentration Fractional Uptake
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