Abstract
Biological responses to various agents, including chemical substances such as drugs, are not constant over time but vary rhythmically; in human beings, as well as in experimental animals circadian rhythms of susceptibility have been demonstrated [1–11] and the number of functions showing such rhythms is rapidly increasing as research progresses.
Maître de Recherches au Centre National de la Recherche Scientifique
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Reinberg, A. (1973). Chronopharmacology. In: Mills, J.N. (eds) Biological Aspects of Circadian Rhythms. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4565-7_4
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