The Relationship between Serum and Salivary Antibodies and Cell-Mediated Immunity in Oral Disease in Man

  • T. Lehner
  • S. J. Challacombe
  • L. Ivanyi
  • J. M. A. Wilton


Immunity to diseases of the mouth shows considerable complexity, as the three principal immune systems, secretory and serum antibodies and cell mediated immunity, can be involved in the development and course of the diseases. Humoral and cellular immune responses to the commensal organisms, as well as to the aggregation of bacteria and their products on the tooth surface (bacterial plaque), have been studied recently. The immune responses to fungal, viral, Gram-positive and Gram-negative organisms in normal subjects, and in patients with the disease these organisms may cause, are worthy of analysis, as they may clarify the factors responsible for protection.


Serum Antibody Bacterial Plaque Streptococcus Mutans Stimulation Index Oral Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • T. Lehner
    • 1
  • S. J. Challacombe
    • 1
  • L. Ivanyi
    • 1
  • J. M. A. Wilton
    • 1
  1. 1.Department of Oral Immunology and MicrobiologyGuy’s Hospital Medical and Dental SchoolsLondonUK

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