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Assembly and Secretion of Immunoglobulin A

  • Chapter
The Immunoglobulin a System

Abstract

Immunoglobulins, like other secreted glycoproteins, are synthesised on membrane-bound polyribosomes, released into the cysternae of the endoplasmic reticulum and pass to the outside via the Golgi apparatus. During passage through the cell there is a stepwise addition of carbohydrate at different subcellular sites, and a general rule is that mannose and hexosamine are added early, whereas fucose and galactose are added late (1,2).

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Author information

Authors and Affiliations

  1. National Institute for Medical Research, London, England

    R. M. E. Parkhouse & E. Della Corte

Authors
  1. R. M. E. Parkhouse
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  2. E. Della Corte
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Editor information

Editors and Affiliations

  1. Institute of Dental Research Departments of Microbiology and Medicine, University of Alabama in Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky

  2. Departments of Pediatrics and Microbiology, University of Alabama in Birmingham, Birmingham, Alabama, USA

    Alexander R. Lawton

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© 1974 Plenum Press, New York

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Parkhouse, R.M.E., Della Corte, E. (1974). Assembly and Secretion of Immunoglobulin A. In: Mestecky, J., Lawton, A.R. (eds) The Immunoglobulin a System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4550-3_15

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  • DOI: https://doi.org/10.1007/978-1-4613-4550-3_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4552-7

  • Online ISBN: 978-1-4613-4550-3

  • eBook Packages: Springer Book Archive

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