Abstract
Testosterone, in large doses, maintains spermatogenesis following hypophysectomy (1,2), suggesting a direct effect on the testis. Androgen target cells in other organs such as prostate (3–8), epididymis (9–14), and seminal vesicles (15) have been shown to contain receptor proteins for 5α-dihydrotestosterone (DHT) and testosterone (T). It is believed that androgenic stimuli to target cells are mediated through such receptor proteins.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ludwig, D.J., Endocrinology 46: 453, 1950.
Desjardins, C., Ewing, C.L., and Irby, D.C., Endocrinology 93: 450, 1973.
Bruchovsky, N., and Wilson, J.D., J. Biol. Chem. 243: 5953, 1968.
Unhjem, O., Tveter, K.J., and Aakvaag, A., Acta Endocrinol., 62: 153, 1969.
Fang, S., Anderson, K.M., and Liao, S., J. Biol. Chem. 244: 6584, 1969.
Mainwaring, W.I.P., J. Endocrinol., 45: 531, 1969.
Baulieu, E.E., and Jung, I., Biochem. Biophys. Res. Commun., 38: 59, 1970.
Rennie, P., and Bruchovsky, N., J. Biol. Chem., 247: 1546, 1972.
Tindall, D.J., French, F.S., and Nayfeh, S.N., Biochem. Biophys. Res. Commun., 49: 1391, 1972.
Tindall, D.J., French, F.S., and Nayfeh, S.N., Biochem. Biophys. Res. Commun., 49: 1391, 1972.
Tindall, D.J., Hansson, V., Sar, M., Stumpf, W.E., French, F.S., and Nayfeh, S.N., Endocrinology 95: 1119, 1974.
Blaquier, J.A., Biochem. Biophys. Res. Commun, 45: 1076, 1971.
Blaquier, J.A., and Calandra, R.S., Endocrinology 93: 51, 1973.
Hansson, V., Djoseland, O., Reusch, E., Attramadal, A., and Torgersen, O., Steroids 22: 19, 1973.
Stern, J.D., and Eisenfeld, A.J., Science 166: 233, 1969.
Blaquier, J.A., and Calandra, R.S., Endocrinology 93: 51, 1973.
Liao, S., and Fang, S., J. Biol. Chem. 246: 16, 1971.
Mainwaring, W.I.P., In: Some Aspects of the Aetiology and Biochemistry of Prostatic Cancer, K. Griffiths, and C.G. Pierrepoint (Eds.), p. 109.
Mainwaring, W.I.P., and Peterken, B.M., Biochem. J. 125: 285, 1971.
Davies, P., and Griffiths, K., Biochem. Biophys. Res. Communc. 53: 373, 1973.
Davies, P., and Griffiths, K., J. Endocrinol. 62: 385, 1974.
Hansson, V., McLean, W.S., Smith, A.A., Tindall, D.J., Weddington, S.C., Nayfeh, S.N., French, F.S., and Ritzen, E.M., Steroids 23: 823, 1974.
Smith, A.A., McLean, W.S., Hansson, V., Nayfeh, S.N., and French, F.S., Steroids 25: 569, 1975.
Smith, A.A., McLean, W.S., Hansson, V., Nayfeh, S.N., and French, F.S., Steroids 25: 569, 1975.
French, F.S., and Ritzen, E.M., Endocrinology 93: 88, 1973.
Hansson, V., Djoseland, O., Reusch, E., Attramadal, A., and Torgersen, O., Steroids, 21: 457, 1973.
Ritzen, E.M., Dobbins, M.C., Tindall, D.J., French, F.S., and Nayfeh, S.N., Steroids 21: 593, 1973.
Hansson, V., Reusch, E., Trygstad, O., Torgersen, O., Ritzen, E.M., and French, F.S., Nature New Biol. 246: 56, 1973.
Vernon, R.G., Kopec, B., and Fritz, I.B., Molec. Cell Endocrinol. 1: 167, 1974.
Hansson, V., Trygstad, O., French, F.S., McLean, W.S., Smith, A.A., Tindall, D.J., Weddington, S.C., Petrusz, P., Nayfeh, S.N., and Ritzen, E.M., Nature 250: 387, 1974.
Sanborn, B.M., Elkington, J.S.H., and Steinberger, E., In: Hormone Binding and Target Cell Activation in the Testis, M. Dufau, and A. Means (Eds.), Plenum Press: New York, 1974, p. 291.
Ingle, D.J., Exper. Med. Surg. 7: 34, 1949.
Hotta, S., and Chaikoff, I.C., Arch. Biochem. Biophys. 56: 28, 1955.
Christensen, A.K., and Mason, N.R., Endocrinology 84: 488, 1969.
Lowry, O.H., Rosebrough, N.S., Farr, A.L., and Randall, A.J., J. Biol. Chem. 193: 265, 1951.
Martin, R.G., and Ames, B.N., J. Biol. Chem. 236: 1372, 1961.
Dingman, C.W. and Peacock, A.C., Biochemistry 7: 659, 1968.
Dingman, C.W. and Peacock, A.C., Biochemistry 7: 659, 1968.
Folch, J., Leese, M., and Stanley, G.H.S., J. Biol. Chem. 226: 499, 1957.
Hansson, V., Steroids 20: 475, 1972.
Mainwaring, W.I.P., and Irving, R., Biochem. J. 134: 113, 1973.
Mainwaring, W.I.P., Mangan, F.R., Wilce, P.A., and Milroy, E.G.P., In: Receptors for Reproductive Hormones, B.W. O’Malley and A.R. Means (Eds.), Plenum Press: New York, 1973.
Mulder, E., Peters, M.J., DeVries, I., and van der Molen, H.J., Molec. Cell. Endocrinol. 2: 171, 1975.
Mulder, E., Van Beurden-Lamers, W.M.O., DeBoer, W., Mechzelsen, M.J., and van der Molen, H.J., F.E.B.S. Letters 47: 209, 1974.
Bruchovsky, N., and Wilson, J.D., J. Biol. Chem. 243:2012, 1968
Mainwaring, W.I.P., and Mangan, F.P., J. Endocrino1. 59: 121, 1973.
Rennie, P., and Bruchovsky, N.J., J. Biol. Chem. 248: 3288, 1973.
Ritzen, E.M., Nayfeh, S.N., French, F.S., and Aronin, P.A., Endocrinology 91: 116, 1972.
Bardin, C.W., Bullock, L.P., Sherins, R.J., Mowszowicz, I., and Blackburn, W.R., Rec. Prog. Hormone Res. 29: 65, 1973.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Plenum Press, New York
About this chapter
Cite this chapter
Smith, A.A., McLean, W.S., Nayfeh, S.N., French, F.S., Ritzen, M. (1975). Androgen Receptor in Rat Testis. In: French, F.S., Hansson, V., Ritzen, E.M., Nayfeh, S.N. (eds) Hormonal Regulation of Spermatogenesis. Current topics in Molecular Endocrinology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4440-7_18
Download citation
DOI: https://doi.org/10.1007/978-1-4613-4440-7_18
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4442-1
Online ISBN: 978-1-4613-4440-7
eBook Packages: Springer Book Archive