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Suppressor Cells in the Embryonic Thymus Mediate Allograft Tolerance

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Immune Reactivity of Lymphocytes

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Abstract

Thymus cells from non-immunized young chickens suppress the allograft rejection in lightly irradiated syngeneic or allogeneic recipients and mediate longlasting skingraft survival in a significant proportion of recipients across a strong histocompatibility difference. Suppressive activity of this kind is already found in the embryonic thymus and is therefore believed to mediate also self tolerance and neonatal allograft tolerance.

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Author information

Authors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstrasse 487, CH-4058, Basel, Switzerland

    Wulf Droege & Margaretha Tuneskog

Authors
  1. Wulf Droege
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  2. Margaretha Tuneskog
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Editor information

Editors and Affiliations

  1. The Weizmann Institute of Science, Israel

    Michael Feldman  & Amiela Globerson  & 

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© 1976 Plenum Press, New York

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Droege, W., Tuneskog, M. (1976). Suppressor Cells in the Embryonic Thymus Mediate Allograft Tolerance. In: Feldman, M., Globerson, A. (eds) Immune Reactivity of Lymphocytes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4355-4_89

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  • DOI: https://doi.org/10.1007/978-1-4613-4355-4_89

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4357-8

  • Online ISBN: 978-1-4613-4355-4

  • eBook Packages: Springer Book Archive

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