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Characterization and Specificity of a T-Cell Cooperative Factor

  • E. Mozes
  • R. Isac
  • D. Givol
  • R. Zakut
  • D. Beitsch

Abstract

One of the central problems in analyzing immune response phenomena, is the mechanism of thymus (T)-bone marrow (B) derived cell interactions. Investigations performed in the past few years resulted in the identification and characterization of various biologically active mediators produced by T cells which are capable of stimulating B cells. Some of these T cell factors have been shown to be antigen-specific (1–3) whereas others are non-specific (4,5), and their functional effects are either-enhancing (1–5) or suppressing (3) antibody production by B cells.

Keywords

Antibody Production Cooperative Activity Cell Supernatant Active Mediator Normal Rabbit Serum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • E. Mozes
    • 1
  • R. Isac
    • 1
  • D. Givol
    • 1
  • R. Zakut
    • 1
  • D. Beitsch
    • 1
  1. 1.Department of Chemical ImmunologyThe Weizmann Institute of ScienceRehovotIsrael

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