Cell Interactions in Immune Responses: Role of T Lymphocytes

  • J. F. A. P. Miller


It is well established that the thymus exerts a widespread influence, not only in the development of immune capacity, but also in the regulation of immune functions. Once differentiated, T cells may become involved in controlling a wide variety of cellular and humoral immune responses by producing quantitative as well as qualitative modifications. Collaboration between lymphocytes has now been documented in both cell-mediated and humoral immunity, i.e. between various subsets of T lymphocytes as well as between T and B cells, as will be evident from the various papers in this Symposium. The T cells can either promote or suppress the function of other lymphocytes, depending on the circumstances, and macrophages often play an essential role in the mediation of lymphocyte interactions.


Human Serum Albumin Spleen Cell Transfer Factor Tolerant Mouse Irradiate Recipient 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • J. F. A. P. Miller
    • 1
  1. 1.Walter and Eliza Hall Institute of Medical ResearchRoyal Melbourne Hospital P.O.MelbourneAustralia

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