Thymocyte Subpopulations as Stimulators in the Mixed Lymphocyte Reaction
Recent studies involving the mixed lymphocyte reaction (MLR) have suggested that genes which map in the I region, and are expressed predominately on B-lymphocytes, are responsible for stimulation of allogeneic responding cells (1). It has been shown, however, that both T- and B-lymphocytes stimulate in the MLR, albeit T-lymphocytes are less stimulatory than B-lymphocytes (2).
KeywordsSpleen Cell Mixed Lymphocyte Reaction Allogeneic Cell Minor Subpopulation Allogeneic Mixed Lymphocyte Reaction
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