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Immunosuppressive Effects of Some Organic Compounds with Anti-Inflammatory Activity

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Chemotherapy

Part of the book series: Chemotherapy ((CT,volume 8))

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Summary

Some indomethacin esters have been tested for immunosuppressive activity and compared with Bleomycin, Mitomycin C, Actinomycin D and Rifamycin SV. The most active substances were actinomycin and an indomethacin-methylen-benzoic ester (IMB-1). It has been seen that IgM response is the most affected when drugs are administered in a short period of time and previously to the antigen.

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Author information

Authors and Affiliations

  1. Inst. “Jaime Ferrán” of Microbiology, C.S.I.C., Madrid, Spain

    I. Barasoain, A. Portoles & J. M. Rojo

  2. Alter Laboratories, Madrid, Spain

    C. Sunkel

Authors
  1. I. Barasoain
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  2. A. Portoles
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  3. J. M. Rojo
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  4. C. Sunkel
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Editor information

Editors and Affiliations

  1. Westminster Hospital and Imperial Cancer Research Fund, UK

    K. Hellmann

  2. Chester Beatty Research Institute, UK

    T. A. Connors

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© 1976 Plenum Press, New York

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Barasoain, I., Portoles, A., Rojo, J.M., Sunkel, C. (1976). Immunosuppressive Effects of Some Organic Compounds with Anti-Inflammatory Activity. In: Hellmann, K., Connors, T.A. (eds) Chemotherapy. Chemotherapy, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4352-3_6

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  • DOI: https://doi.org/10.1007/978-1-4613-4352-3_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4354-7

  • Online ISBN: 978-1-4613-4352-3

  • eBook Packages: Springer Book Archive

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