Chemotherapy pp 215-218 | Cite as

Collateral Sensitivity between an Alkylating Agent and Halogenated Methotrexate

  • Brian W. Fox
Part of the Chemotherapy book series (CT, volume 8)


We have established four cell lines designated YMDR6 to YMDR9 by in vivo subthreshold treatment of Yoshida lymphosarcoma with methylene dimethanesulphonate (MDMS). These have been transferred to cell culture and grown continuously. Only YMDR8 was cloned.


Resistant Cell Line Nitrogen Mustard Methane Sulphonate Drug Pair Collateral Sensitivity 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Brian W. Fox
    • 1
  1. 1.Paterson LaboratoriesManchesterUK

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