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Oestrogen Binding as a Predictive Test for DMBA-Induced Tumour Response to Tamoxifen Therapy

  • V.C. Jordan
  • T. Jaspan

Abstract

Jensen et al, (1971) have suggested that oestrogen receptor assays may be a useful predictive test to determine the oestrogen dependency of breast tumours. In the laboratory, the 7,12dimethylbenz(a)anthracene (MBA)-induced rat mammary carcinoma (Huggins et al. 1961) provides a model for the study of this theory, since oestrogen binding in the tumour has been reported to be related to oestrogen dependency (Mobbs 1966, McGuire & Julian 1971, Mobbs & Johnson 1974).

Keywords

Oestrogen Receptor Tamoxifen Therapy Predictive Test Oestrogen Binding Oestrogen Receptor Negative Tumour 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • V.C. Jordan
    • 1
  • T. Jaspan
    • 1
  1. 1.Department of PharmacologySchool of MedicineLeedsUK

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